Diagnosis and Management of Candida and Other Fungal Infections of the Head and Neck |
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Authors: | Miller David J |
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Institution: | (1) Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, 53706 Madison, WI, USA |
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Abstract: | Fungi are common inhabitants of the oral and nasal mucosa, and therefore the differentiation between colonization and pathogenicity
in the setting of upper respiratory tract infection symptoms can be difficult. Fungal head and neck infections occur in both
immunocompetent and immunocompromised persons, and patients with neutropenia, diabetes mellitus, corticosteroid use, and HIV
infection are particularly susceptible to serious and potentially life-threatening infections. Invasive fungal head and neck
infections generally require extensive surgical debridement and prolonged systemic antifungal therapy, and frequently carry
a poor prognosis when the underlying immunosuppression cannot be corrected. In contrast, noninvasive fungal head and neck
infections often respond to short courses of systemic or topical antifungal therapy, or require limited surgical debridement
alone. |
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