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溶栓和抗凝方案治疗肺栓塞疗效分析
引用本文:马成花. 溶栓和抗凝方案治疗肺栓塞疗效分析[J]. 中国医院用药评价与分析, 2008, 8(10): 770-772
作者姓名:马成花
作者单位:青海省人民医院药剂科,西宁市,810007
摘    要:目的:尿激酶溶栓方案和低分子肝素抗凝方案治疗肺栓塞疗效的评价。方法:收集41名肺栓塞患者治疗资料,回顾性分析溶栓治疗和抗凝治疗的疗效,比较两组患者呼吸困难、胸痛等症状缓解率以及血气指标改善情况等。结果:与抗凝治疗组相比,溶栓治疗组患者呼吸困难、胸痛、咳嗽、咳血和紫绀缓解率均高于抗凝治疗组(P〈0.1),治疗有效率高于抗凝治疗组(P〈0.05)。结论:依本次实验结果可认为尿激酶溶栓治疗疗效优于低分子肝素抗凝治疗,

关 键 词:尿激酶  低分子肝素  肺栓塞  疗效评价

Thrombolytic Therapy versus Anticoagulant Therapy for Pulmonary Embolism:Evaluation of Therapeutic Efficacy
MA Cheng-hua. Thrombolytic Therapy versus Anticoagulant Therapy for Pulmonary Embolism:Evaluation of Therapeutic Efficacy[J]. Evaluation and Analysis of Drug-Use in Hospital of China, 2008, 8(10): 770-772
Authors:MA Cheng-hua
Affiliation:MA Cheng-hua (Qinghai Provincial People's Hospital, Xining 810007, China)
Abstract:OBJECTIVE: To evaluate the clinical efficacy of thrombolytic therapy with Urokinase versus anticoagulant therapy with Low Molecular Heparin in the treatment of pulmonary embolism. METHODS: The clinical records of 41 patients with pulmonary embolism were collected and the efficacy of thrombolytic therapy versus anticoagulant therapy in dyspnea and chest pain and the blood gas indexes were analyzed retrospectively. RESULTS: Compared with the anticoagulant therapy group, the remission rates of dyspnea, chest pain, cough, hemoptisis and cyanosis were all significantly higher ( P 〈 0.1 ) and the effective rate was also higher ( P 〈 0.05) in the thrombolytic therapy group. CONCLUSION : The results suggest that the therapeutic efficacy of thrombolytic therapy with Urokinase is higher than that of anticoagulant therapy with Low Molecular Heparin in the treatment of pulmonary embolism.
Keywords:Urokinase  Low molecular heparin  Pulmonary embolism  Evaluation of therapeutic efficacy
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