|
|||||
|
|
Nutritional supplementation with transforming growth factor-beta inhibits intestinal adaptation after massive small bowel resection in a rat |
|
| Authors: | Igor Sukhotnik Jorge G. Mogilner Shani Ben Lulu Yulia Bashenko Ron Shaoul Elena Chemodanov Arnold G. Coran |
| Affiliation: | (1) Laboratory of Intestinal Adaptation and Recovery, The Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;(2) Department of Pediatric Surgery B, Bnai Zion Medical Center, 47 Golomb St., P.O.B 4940, 31048 Haifa, Israel;(3) Department of Pathology, Bnai Zion Medical Center, Haifa, Israel;(4) Pediatric Gastroenterology and Nutrition Unit, Meyer Children’s Hospital, Rambam Medical Center, Haifa, Israel;(5) Section of Pediatric Surgery, C.S. Mott Children’s Hospital and University of Michigan Medical School, Ann Arbor, MI, USA |
| Abstract: | IntroductionTransforming growth factor beta (TGF-β) has been shown to affect epithelial cell differentiation and proliferation through epithelial-mesenchymal and epithelial-immune cell interaction. In the present study, we evaluated the effect of TGF-β2-enriched polymeric diet (Modulen) on enterocyte turnover in a rat model of short bowel syndrome (SBS). |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |