纳晶微针导入氨甲环酸联合皮肤镜治疗黄褐斑的效果

目的 探究纳晶微针导入氨甲环酸联合皮肤镜在黄褐斑患者治疗中的应用效果。方法 选取2022年 6月-2023年6月本院收治的70例黄褐斑患者为研究对象，随机分为对照组和观察组，每组35例。对照组给予 氨甲环酸口服治疗，观察给予纳晶微针导入氨甲环酸联合皮肤镜治疗，比较两组临床疗效、黄褐斑严重程度指 数（MASI评分）、医生整体评价（PGA评分）、满意度及皮损积分。结果 观察组治疗总有效率为94.29%，高 于对照组的77.14%（P ＜0.05）；观察组治疗后MASI评分、PGA评分均低于对照组（P＜0.05）；观察组满意度 为97.14%，高于对照组的80.00%（P＜0.05）；观察组治疗后皮损总积分低于对照组（P ＜0.05）。结论 纳晶 微针导入氨甲环酸联合皮肤镜治疗黄褐斑的效果良好，可有效改善黄褐斑严重程度，减轻皮损症状，促进 恢复，有利于提高患者满意度。

Effect of Nanocrystal Microneedle Introduction of Tranexamic Acid Combined with Dermoscopyin the Treatment of Chloasma

Objective To explore the application effect of nanocrystalline microneedle introduction of tranexamic acid combined with dermoscopy in the treatment ofpatientswith chloasma. Methods A total of 70 patients with chloasma admitted to our hospital from June 2022 to June 2023 were randomly divided into control group and observation group, with 35 patients in each group. The control group was treated with oral tranexamic acid, and the observation group was treated with nanocrystal microneedle introduction of tranexamic acid combined with dermoscopy. The clinical efficacy, melasma severity index (MASI score), patient global assessment (PGA score), satisfaction and skin lesion score were compared between the two groups. Results The total effective rate of treatment in the observation group was 94.29%, which was higher than 77.14% in the control group (P <0.05). After treatment, the MASI score and PGA score of the observation group were lower than those of the control group (P <0.05). The satisfaction rate of the observation group was 97.14%, which was higher than 80.00% of the control group (P <0.05). After treatment, the total skin lesion score of the observation group was lower than that of the control group (P <0.05). Conclusion Nanocrystalline microneedle introduction of tranexamic acid combined with dermoscopy has a good effect in the treatment of chloasma, which can effectively improve the severity of chloasma, reduce the symptoms of skin lesions, promote recovery, and improve patient satisfaction.