PCI对慢性稳定性冠心病患者血管内皮功能、 血清hs-CRP水平的影响

目的 探讨经皮冠状动脉介入术治疗慢性稳定性冠心病的疗效及对患者血管内皮功能、血清hs-CRP水平的影响。方法 收集我院自2015年9月~2017年10月收治的慢性稳定性冠心病患者120例作为观察对象，按治疗方式的不同分为观察组与对照组，每组60例。对照组给予冠状动脉旁路移植术（CABG）治疗，观察组则给予PCI治疗。观察并比较两组治疗有效率，血管内皮功能、血清hs-CRP水平变化情况。结果 观察组治疗总有效率为91.67%，高于对照组的76.67%，差异有统计学意义（P＜0.05）。观察组血管内皮功能相关指标及血清hs-CRP水平优于对照组，差异有统计学意义（P＜0.05）。结论 PCI治疗慢性稳定性冠心病疗效显著，可快速恢复患者血管内皮功能及血清hs-CRP水平，安全有效。

Effect of PCI on Vascular Endothelial Function and Serum hs-CRP Levels in Patients with Chronic Stable Coronary Heart Disease

Abstract:Objective To investigate the efficacy of percutaneous coronary intervention in the treatment of chronic stable coronary heart disease and its effect on endothelial function and serum hs-CRP levels.Methods A total of 120 patients with chronic stable coronary heart disease who were admitted to our hospital from September 2015 to October 2017 were collected as observation objects. According to the treatment methods,they were divided into observation group and control group,with 60 cases in each group.The control group received coronary artery bypass grafting(CABG)and the observation group received PCI.Observe and compare the therapeutic efficacy,vascular endothelial function and serum hs-CRP levels in the two groups.Results The total effective rate of observation group was 91.67%,which was higher than 76.67% of the control group,the difference was statistically significant(P<0.05). The related indicators of vascular endothelial function and serum hs-CRP levels in the observation group were better than those in the control group,and the difference was statistically significant(P<0.05).Conclusion PCI has a significant effect on the treatment of chronic stable coronary artery disease.It can quickly restore the vascular endothelial function and serum hs-CRP levels,which is safe and effective.