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慢性阻塞性肺疾病急性加重期与慢性阻塞性肺疾病并发社区获得性肺炎患者的临床对比
引用本文:许 俊. 慢性阻塞性肺疾病急性加重期与慢性阻塞性肺疾病并发社区获得性肺炎患者的临床对比[J]. 医学信息, 2018, 0(22): 118-120. DOI: 10.3969/j.issn.1006-1959.2018.22.033
作者姓名:许 俊
作者单位:(东南大学附属中大医院溧水分院/南京市溧水区人民医院呼吸内科,江苏 南京 211200)
摘    要:目的 探究慢性阻塞性肺疾病急性加重期与慢性阻塞性肺疾病并发社区获得性肺炎患者的临床对比,旨在为临床的诊断和治疗提供科学依据。方法 选取2017年3月~2018年3月于我院接受治疗的82例COPD患者为研究对象,按照随机数表法分为两组,其中观察组42例为AECOPD患者,对照组40例为COPD合并CAP患者,比较两组患者的临床症状、肺功能以及PCT、CRP水平。结果 观察组患者呼吸困难、咳脓痰、精神差、发热等临床症状的发生率均低于对照组,差异具有统计学意义(P<0.05)。观察组患者FEV1、FVC、FEV1/FVC分别为(64.15±7.26)ml、(62.85±7.29)ml、(62.03±5.54)%,均高于对照组的(52.51±5.75)ml、(50.85±6.74)ml、(52.34±5.61)%,差异具有统计学意义(P<0.05)。观察组患者PCT和CRP分别为(0.52±0.07)ng/L和(21.51±1.35)mg/L,均低于对照组的(0.97±0.08)ng/L和(40.05±1.57)mg/L,差异具有统计学意义(P<0.05)。结论 AECOPD患者与COPD合并CAP患者相比,临床症状发生情况较少,肺功能较好,对患者进行相关检测,能够提高治疗效果。

关 键 词:慢性阻塞性肺疾病  慢性阻塞性肺疾病急性加重期  社区获得性肺炎  肺功能

Clinical Comparison of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Chronic Obstructive Pulmonary Disease Complicated with Community Acquired Pneumonia
XU Jun. Clinical Comparison of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Chronic Obstructive Pulmonary Disease Complicated with Community Acquired Pneumonia[J]. Medical Information, 2018, 0(22): 118-120. DOI: 10.3969/j.issn.1006-1959.2018.22.033
Authors:XU Jun
Affiliation:(Lishui Branch Hospital,Zhongda Hospital Affiliated to Southeast University/Department of Respiratory Medicine,People's Hospital of Lishui District,Nanjing 211200,Jiangsu,China)
Abstract:Objective To investigate the clinical comparison between patients with acute exacerbation of chronic obstructive pulmonary disease and patients with chronic obstructive pulmonary disease complicated with community-acquired pneumonia, aiming at providing scientific evidence for clinical diagnosis and treatment. Methods 82 patients with COPD who were treated in our hospital from March 2017 to March 2018 were enrolled in the study. They were divided into two groups according to the random number table. Among them, 42 patients in the observation group were AECOPD patients,40 patients in the control group were treated with COPD and CAP. The clinical symptoms, lung function, and PCT and CRP levels were compared between the two groups. Results The incidence of clinical symptoms such as dyspnea, cough and sputum, mental retardation and fever were lower in the observation group than in the control group, the difference was statistically significant (P<0.05). The FEV1, FVC and FEV1/FVC of the observation group were (64.15±7.26) ml, (62.85±7.29) ml, and (62.03±5.54)%, respectively, which were higher than the control group (52.51±5.75) ml, (50.85±6.74)ml, (52.34±5.61)%, the difference was statistically significant (P<0.05). The PCT and CRP of the observation group were (0.52±0.07) ng/L and (21.51±1.35) mg/L, respectively, which were lower than those of the control group (0.97±0.08) ng/L and (40.05±1.57) mg/L,the difference was statistically significant (P<0.05). Conclusion Compared with patients with COPD and CAP, AECOPD patients have fewer clinical symptoms and better lung function. Relevant tests can improve the treatment effect.
Keywords:Chronic obstructive pulmonary disease  Acute exacerbation of chronic obstructive pulmonary disease  Community acquired pneumonia  Pulmonary function
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