黛力新联合维生素B6治疗伴负性情绪的功能性消化不良临床疗效研究

目的 探讨黛力新联合维生素B6片辅助治疗伴负性情绪的功能性消化不良的临床效果, 为功能性消化不良（FD）的临床治疗提供参考。方法 选择云浮市人民医院2016年6月~2018年1月收治的112例伴有抑郁焦虑等负性情绪的FD患者，采用随机数字表法分为观察组和对照组，每组56例，两组患者均给予常规基础治疗，观察组患者在常规治疗的基础上给予黛力新（氟哌噻吨美利曲辛片）、维生素B6片口服治疗，对两组患者治疗后的心理状态采用SDS及SAS量表进行评估，并对躯体症状、总体疗效进行比较和分析。结果 观察组患者SAS评分、SDS评分低于对照组（P＜0.05)；观察组患者躯体症较前缓解（P＜0.05），且治疗组各项评分低于对照组（P＜0.05），观察组治疗总有效率为 92.72%，对照组治疗总有效率为68.52%，差异具有统计学意义（P＜0.05)。结论 对于伴情绪障碍的FD患者，在常规治疗基础上加用氟哌噻吨美利曲辛片联合维生素B6片治疗，可有效减轻患者精神和躯体症状，提高临床疗效。

Efficacy of Deanxit and VitB6 tablets in management of negative emotions in patients with Functional dyspepsia

Objective To investigate the clinical effect of Deanxit combined with vitamin B6 in the treatment of functional dyspepsia with negative emotion, and to provide reference for the clinical treatment of functional dyspepsia(FD). Methods 112 cases of FD patients with negative emotions such as depression and anxiety were selected from Yunfu People's Hospital from June 2016 to January 2018. They were randomly divided into observation group and control group, 56 cases in each group. The patients in the group were given routine basic treatment. The patients in the observation group were given Deanxit (Flupentixol and Melitracen Tablets) tablets and vitamin B6 tablets on the basis of conventional treatment.The psychological status of the two groups of patients after treatment was assessed by SDS and SAS scales, and the physical symptoms and overall efficacy were compared and analyzed. Results The SAS score and SDS score of the observation group were lower than those of the control group(P<0.05). The physical symptoms of the observation group were lower than those of the control group(P<0.05), and the scores of the treatment group were lower than the control group (P<0.05). The total effective rate was 92.72% in the treatment group and 68.52% in the control group,the difference was statistically significant (P<0.05). Conclusion For patients with FD with mood disorders, the addition of Flupentixol and Melitracen Tablets combined with vitamin B6 tablets on the basis of conventional treatment can effectively reduce the mental and physical symptoms of patients and improve clinical efficacy.