| 艰难梭菌感染的流行病学及危险因素 |
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| 引用本文： | 罗雨欣,韩菲,张瑞苗,尹凤荣. 艰难梭菌感染的流行病学及危险因素[J]. 临床荟萃, 2018, 33(5): 369. DOI: 10.3969/j.issn.1004-583X.2018.05.001 |
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| 作者姓名： | 罗雨欣 韩菲 张瑞苗 尹凤荣 |
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| 作者单位： | 河北医科大学第二医院消化内科，河北省消化病重点实验室，河北省消化病研究所，河北 石家庄 050000 |
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| 摘 要： | 艰难梭菌(Clostridium difficile，CD)是一种寄生于肠道的革兰阳性梭状芽孢杆菌。随着抗生素的广泛应用，艰难梭菌感染（Clostridium difficile infection，CDI）的发病率在全球范围内逐年升高。尤其是CD高产毒株（BI/NAP1/027/毒素Ⅲ型）的出现和流行，使得CD成为近年来医疗卫生相关的重要病原菌之一。目前，国内外有关CDI流行病学方面的研究不断更新。本文对CDI的流行病学情况及危险因素进行综述，旨在提高临床医务工作者对CDI的认识。
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| 关 键 词： | 梭菌感染 流行病学 危险因素 |
Epidemiology and risk factors of Clostridium difficile infection |
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| Luo Yuxin,Han Fei,Zhang Ruimiao,Yin Fengrong. Epidemiology and risk factors of Clostridium difficile infection[J]. Clinical Focus, 2018, 33(5): 369. DOI: 10.3969/j.issn.1004-583X.2018.05.001 |
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| Authors: | Luo Yuxin Han Fei Zhang Ruimiao Yin Fengrong |
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| Affiliation: | Department of Gastroenterology, the Second Hospital of Hebei Medical University; Hebei Key Laboratory ;of Gastroenterology; Hebei Institute of Gastroenterology, Shijiazhuang 050000, China |
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| Abstract: | Clostridium difficile (CD), parasitic on the intestine, belongs to gram positive bacteria. With the widespread use of antibiotics, the incidence and severity of Clostridium difficile infection (CDI) have been on the rise worldwide. Of particular note, the emergence and outbreak of virulent ribotype 027 strain (BI/NAP 1/027/toxin Ⅲ) has made CD one of the most important healthcare related pathogens. Researches on CDI epidemiology are undergoing continuous renewal at home and abroad. The epidemiological situation and risk factors of CDI are reviewed in order to strengthen the understanding of CDI among clinical medical workers． |
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| Keywords: | Clostridium infections；epidemiology；risk factors |
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