脑电双频谱指数指导下的临床麻醉深度研究

目的 研究脑电双频谱指数指导下的全身麻醉深度及管理。方法 选择2016年12月~2017年6月择期胃肠外科开腹手术患者60例，随机分为两组,每组30例，P组为丙泊酚治疗，F组为芬太尼类镇痛药治疗，观察两组基础值，意识消失，插管，插管后30 s，进腹腔，手术结束的BIS、MAP、SBP和HR。结果 两组患者诱导前基础BIS、SBP、MAP、HR，差异无统计学意义（P＞0.05）；意识消失时间，意识消失时BIS差异无统计学意义（P＞0.05），意识消失时的丙泊酚用量差异有统计学意义（P＜0.05）；两组中，与插管时相比，插管后30 s，进腹腔时BIS、SBP、MAP差异有统计学意义（P＞0.05），HR无统计学意义（P＞0.05）；手术结束时两组BIS差异有统计学意义（P＞0.05）,HR、SBP、MAP无统计学差异（P＞0.05）。结论 临床意义的麻醉深度是具有相对性的，依手术刺激大小而定，麻醉过程中可通过调节麻醉性镇痛药物用量来维持麻醉深度。

Study on the Depth of Clinical Anesthesia Guided by Bispectral Index of EEG

Abstract:Objective To study the depth and management of general anesthesia under the guidance of bispectral index of EEG. Methods 60 patients undergoing elective gastrointestinal surgery from December 2016 to June 2017 were randomly divided into two groups.30 patients in each group,group P was treated with propofol, group F was fentanyl analgesic treatment.The basic values of two groups were observed,consciousness disappeared,intubation,30 s after intubation,abdominal cavity,BIS,MAP,SBP and HR at the end of operation.Results There was no significant difference in baseline BIS,SBP,MAP and HR between the two groups before induction(P> 0.05).There was no significant difference in the time of consciousness disappearance and the loss of consciousness when there was no consciousnes (P>0.05).There was a statistically significant difference in the dosage of propofol when consciousness disappeared(P< 0.05).In two groups,compared with intubation,after intubation 30 s,BIS and SBP into abdominal cavity and MAP had significant difference(P>0.05),HR had no statistical significance(P>0.05);at the end of the operation of BIS in the two groups had significant difference(P>0.05),no significant difference between HR and SBP and MAP(P>0.05).Conclusion The depth of clinical anesthesia is relative,depending on the size of the operation stimulus.During anesthesia,we can adjust the dosage of narcotic analgesics to maintain the depth of anesthesia.