曲美他嗪联合琥珀酸美托洛尔治疗冠心病心力衰竭疗效观察

目的 观察冠心病心力衰竭患者施予曲美他嗪与琥珀酸美托洛尔联合治疗的效果。方法 将本院收治的120例冠心病心力衰竭患者随机分为A组与B组，各60例。A组行常规治疗，B组在A组基础上施予曲美他嗪与琥珀酸美托洛尔联合治疗，比较两组的临床疗效及治疗前后患者的心肌功能情况。结果 治疗后B组患者LVEDD、LVESD、DBF、SBF低于A组，LVEF高于A组，差异有统计学意义（P＜0.05）；A组总有效率为81.67%，低于B组的96.67%，差异有统计学意义（P＜0.05）。结论 曲美他嗪与琥珀酸美托洛尔联合治疗冠心病心力衰竭，临床效果显著，可有效改善患者心肌功能。

Therapeutic Effect of Trimetazidine Combined with Metoprolol Succinate in the Treatment of Coronary Heart Disease with Heart Failure

Abstract:Objective To observe the effect of combined treatment with trimetazidine and metoprolol succinate in patients with coronary heart disease and heart failure.Methods 120 patients with coronary heart disease admitted to our hospital were randomly divided into group A and group B,60 cases in each group.Group A was treated routinely.Group B was treated with combination of trimetazidine and metoprolol succinate on the basis of group A.The clinical efficacy of the two groups and the myocardial function of the patients before and after treatment were compared.Results After treatment,LVEDD,LVESD,DBF and SBF were lower in group B than in group A,and LVEF was higher than that in A group,the difference was statistically significant(P<0.05),and the total effective rate of group A was 81.67%,lower than that of group B 96.67%,and the difference was statistically significant(P<0.05).Conclusion Trimetazidine combined with metoprolol succinate is effective in treating coronary heart disease with heart failure.It can effectively improve myocardial function in patients with coronary heart disease.