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粪菌移植在艰难梭菌感染治疗中的应用
引用本文:向丽园,张发明. 粪菌移植在艰难梭菌感染治疗中的应用[J]. 临床荟萃, 2018, 33(5): 385. DOI: 10.3969/j.issn.1004-583X.2018.05.00
作者姓名:向丽园  张发明
作者单位:1.南京医科大学第二附属医院消化医学中心,江苏 南京 210011; 2.南京医科大学附属逸夫医院 微生态治疗科,江苏 南京 211166
基金项目:国家自然科学基金(81600417);江苏省创新团队;肠病研究基金(公益捐赠)
摘    要:粪菌移植(Fecal microbiota transplantation, FMT)已被美国医学指南、欧洲专家共识推荐用于成人复发性艰难梭菌感染(Clostridium difficile infection, CDI)。本文主要就FMT治疗CDI的适应证、临床流程、安全性、伦理与监管等的研究进展及中国医生的治疗选择进行综述。

关 键 词:梭菌感染  移植  粪菌  

Application of fecal microbiota transplantation in treatment of Clostridium difficile infection
Xiang Liyuan,Zhang Faming. Application of fecal microbiota transplantation in treatment of Clostridium difficile infection[J]. Clinical Focus, 2018, 33(5): 385. DOI: 10.3969/j.issn.1004-583X.2018.05.00
Authors:Xiang Liyuan  Zhang Faming
Affiliation:1.Medical Center for Digestive Diseases, the Second Affiliated Hospital of Nanjing Medical University, ;Nanjing 210011, China;  2.Department of Microbiotherapy, Sir Run Run Hospital at ;Nanjing Medical University, Nanjing 211166, China
Abstract:Fecal microbiota transplantation (FMT) has been recommended by American Medical Guideline and European Expert Consensus to treat recurrent Clostridium difficile infection (CDI). This article aims to review the research advancement of indications, clinical workflow, safety, and ethics of and supervision on FMT in the treatment of CDI and the concerned treatment options of Chinese doctors.
Keywords:Clostridium infections  transplantation  fecal microbiota   
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