攀枝花市2013年和2015年健康人群麻疹抗体水平监测分析

目的 了解攀枝花市近年来健康人群麻疹抗体水平情况,为评估麻疹疫情风险,调整免疫策略提供依据。方法 采用酶联免疫吸附法(ELISA)定量检测攀枝花市健康人群麻疹IgG抗体水平,采用SPSS22.0进行 χ2检验。结果 2013年和2015年分别采集有效血清样本706份和682份,麻疹IgG抗体阳性率分别是84.84％、87.24％;不同年龄段、不同接种情况人群抗体阳性率差异有统计学意义。2013年和2015年各年龄组抗体阳性率之间差异有统计学意义( Ｐ〖WTBZ〗均＜0.05)。两年间均是＜1岁组、1岁～组抗体水平较低,且2015年15～岁组及≥20岁组抗体水平较低。2015年,全人群、15岁以下人群与3～15岁人群的麻疹疫苗接种率差异有统计学意义( Ｐ〖WTBZ〗＜0.05)。2015年,全人群与15岁以下人群接种两剂次及以上麻疹疫苗的人群抗体阳性率均大于只接种一剂麻疹疫苗、未接种麻疹疫苗和接种记录不详的人群。结论 抗体水平低的人群是麻疹发病的高危人群,低年龄组及成人麻疹抗体水平较低且麻疹高发,是攀枝花市麻疹防控的重点人群。

Measles antibody level among healthy population in Panzhihua,2013-2015

Objective To understand the measles antibody level of healthy population in recent years in Panzhihua City,and to provide basis for the assessment of measles outbreaks risk and adjustment of immune strategy. Methods The antibody level of measles IgG was detected by enzyme-linked immunosorbent assay(ELISA).Chi-square test was adopted in SPSS22.0 statistical software. Results In 2013 and 2015,706 and 682 effective serum samples were collected respectively,and the positive rates of IgG were 84.84% and 87.24% respectively.Positive rates of antibody in different age groups and different inoculation population were significantly different.Between 2013 and 2015,the positive rates of antibody in each age group were significantly different(P<0.001).The two-year-old group was lower than the 1-year-old group.The antibody level of the age of 1~was low,and the antibody level of 15-year-old age and 20 or above group were low in 2015.Compared with other age groups,the difference was statistically significant(P<0.001).In 2015,the positive rates in whole-population and 15 years old and below age group with two doses vaccination and above were higher than that had only one dose vaccination,non- vaccination and unknown records. Conclusion People who have low antibody level have high risk for measles.Low age group and adult shows low level of measles antibody,so they have high incidence of measles.It's necessary to strength prevention and control for people with low measles antibody levels.