三种方法对恶性胸腔积液诊断价值的比较

目的：比较胸腔积液（胸液）细胞学、胸膜活检、胸液块状凝集物（凝集块）３种病理标本的获取主对恶性胸液的诊断阳性率。探讨３种方法应用的诊断价值。方法：对４４例已确诊的恶性肿瘤合并胸液做的病人，经皮针刺胸膜活检后，置入细导管引流，收集胸液中凝集块行是学检查，同时送胸液做细胞学检查。结果：胸液凝集块阳性率为９０．２４％，癌组织类型确定率为１００％，与胸液细胞学以及胸膜活检相比，均有显著性差异（Ｐ〈０．０５

Three Methods Combination in the Diagnosis of Malignant Pleural effusion

Objective:To compare pleural effusion cytology,pleural biopsy, the coagulum of pleural effusion with their positive diag-nostic rates of malignant pleural effusion; to explore the value of the three methods combination. Methods:44 patients with documented malignant carcinoma complicated with pleural effusion underwent pleural biopsy,and had thin chest tube intu-bated to drain and the coagulum collected which was cut and checked by microscopy. At the same time,cytology was under-went . Results: The positive rate of coagulum was 90.24% , and the type diagnostic rate of cancer tissue was 100% . There were significant differences between coagulum and cytology,pleural biopsy(P<0.005,P<0.01,P<0.005,P<0.05 re-spectively). The positive rate of three methods combination was 95.12%. Conclusions:The coagulum of pleural effusion checked by microscopy had a highly positive rate for type diagnosis. The three methods combination can significantly im-prove the positive rate of malignant pleural effusion.