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Concurrent metastatic thymic carcinoma and postirradiation sarcoma
Authors:Chen Tzu-Ju  Lu Hung-I  Huang Cheng-Hua  Hsu Hsuan-Chih  Chen Sung-Ting  Chen Wei-jen  Huang Chao-Cheng
Affiliation:Department of Pathology, Kaohsiung Medical University Hospital and Kaohsiung Medical University, Kaohsiung, Taiwan.
Abstract:We present a case of concurrent metastatic thymic carcinoma and postirradiation sarcoma in the same lobe of the lung in a woman who had received partial resection of thymic carcinoma with chemoradiotherapy 11 years ago. One tumor showed similar histology to the previous carcinoma. The other tumor was a pleomorphic sarcoma, suggestive of a postirradiation sarcoma. Irradiation-induced sarcomas are rare and have not been reported in patients with thymic carcinoma. This case may serve as a model in considering the possibility of postirradiation sarcoma for patients encountering recurrent masses with the history of radiotherapy for thymic carcinoma several years ago.
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