肿瘤标志物联合MRCP对肝外胆道梗阻的临床应用研究

评价肿瘤标志物与MRCP联合对肝外胆道梗阻的鉴别诊断价值.采用化学发光免疫分析法测定97例肝 外胆道梗阻患者血清CA19-9、CA125及CEA水平,行MRCP显像并进行统计分析.CA19-9在恶性梗阻时的阳 性率明显高于CEA和CA125(P<0.01),与MRCP联合检查,诊断准确性可达100%.血清CA19-9检测与 MRCP结合鉴别诊断肝外胆道梗阻不仅能提供精确的定位信息,而且可以进行准确的定性判断;CEA和CA125 还可以为恶性梗阻的腹腔转移提供可靠信息.

Clinical Application of Tumor Markers Combined with MRCP in Extrahepatic Biliary Obstruction

To evaluate the value of serum tumor markers combined with MRCP in differentiate diagnosis of extrahepatic biliary obstruction,the serum levels of CA19-9,CA125 and CEA in 97 patients with extrahepatic biliary obstruction were measured by chemiluminescence immunoassay.MRCP were applied at the same time.The results showed that the positive rate of CA19-9 was significantly higher than that of CA125 and CEA in malignant obstructions(P<0.01).Combined with MRCP,the accuracy rate of diagnose was significantly high(100%).The combination detection of CA19-9 and MRCP has important value in the differentiate diagnosis of extrahepatic biliary obstruction to provide excellent accuracy information about the locations of biliary obstructions.The serum levels of CEA and CA125 also provide information of metastasis in malignant obstructions.