| 2型糖尿病肾病与ACE基因多态性的相关性研究 |
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| 引用本文： | 丁蔷薇,马亚楠,江新泉.2型糖尿病肾病与ACE基因多态性的相关性研究[J].泰山医学院学报,2012,33(5):358-359. |
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| 作者姓名： | 丁蔷薇 马亚楠 江新泉 |
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| 作者单位： | 泰山医学院公共卫生学院,山东,泰安,271016 |
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| 基金项目： | 泰安市大学生科技创新计划课题 |
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| 摘 要： | 目的 探讨血管紧张素转换酶(ACE)基因多态性与泰安地区汉族2型糖尿病肾病(DN)的关系.方法 应用聚合酶链反应技术对2-型糖尿病肾病(DN)及正常对照组进行了ACE基因多态性分析.结果 DM组和DN组与正常对照组之间基因型分布无显著性差异,ACE基因插入/缺失多态性与DN的发生之间无相关性.结论 ACE基因插入/缺失多态性与DN的发生无关.
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| 关 键 词： | 糖尿病肾病 ACE基因 多态性 |
Association relationship between type II diabetic nephropathy with angiotensin converting enzyme |
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| DING Qiang-wei
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MA Ya-nan
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JIANG Xin-quan.Association relationship between type II diabetic nephropathy with angiotensin converting enzyme[J].Journal of Taishan Medical College,2012,33(5):358-359. |
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| Authors: | DING Qiang-wei MA Ya-nan JIANG Xin-quan |
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| Institution: | (School of Public Health,Taishan Medical College,Taian 271016,China) |
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| Abstract: | Objective: To study the relationship between angiotensin converting enzyme(ACE) gene polymorphism and type II diabetic nephropathy(DN) in Tai’an region.Methods: Analysis was done of the type II diabetic nephropathy(DN) and the normal control group ACE gene polymorphism by polymerase chain reaction technology.Results: There was no significant difference in ingenotye distribution among DM group,DN group and normal control group.Conclusion: There is no relationship between the ACE gene insertion/deletion polymorphism and the occurrence of DN. |
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| Keywords: | diabetic nephropathy angiotensin converting enzyme polymorphism |
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