| 原发性肝癌介入治疗的药代动力学研究现状 |
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| 引用本文： | 敖劲,张跃伟. 原发性肝癌介入治疗的药代动力学研究现状[J]. 介入放射学杂志, 2011, 20(9): 749-752 |
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| 作者姓名： | 敖劲 张跃伟 |
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| 作者单位： | 1. 遵义医学院附属医院介入科,贵州,563003
2. 大连大学附属中山医院介入科 |
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| 摘 要： | 近年来,栓塞剂成为TACE治疗肝癌的讨论热点之一.各种各样的栓塞剂用来提高TACE的疗效,从不规则型到微球,再到载药微球,目的 在于提高肿瘤局部化疗药浓度,降低外周血药浓度,增加抗肿瘤的疗效,降低化疗药的毒性.本文就肝癌不同介入治疗方法的药代动力学变化特性进行回顾.
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| 关 键 词： | 肝癌 介入治疗 药代动力学 |
The pharmacokinetics of the drugs used in interventional therapy for Primary liver cancer: its current situation in research |
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| AO Jin,ZHANG Yue-wei. The pharmacokinetics of the drugs used in interventional therapy for Primary liver cancer: its current situation in research[J]. Journal of Interventional Radiology, 2011, 20(9): 749-752 |
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| Authors: | AO Jin ZHANG Yue-wei |
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| Affiliation: | AO Jin,ZHANG Yue-wei.Department of Interventional Radiology,Affiliated Hospital of Zunyi Medical College,Zunyi,Guizhou Province 563003,China |
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| Abstract: | For recent years,embolization agents has become one of the hot points in the discussion concerning transcatheter hepatic arterial chemoembolization(TACE) for liver carcinomas.A variety of embolic agents have been developed in order to improve the therapeutic effect of TACE.The embolic agents now used in TACE include irregular particles,spherical microspheres,drug-eluting microspheres,etc.The development of embolic agents is aimed at increasing the chemotherapy drug concentration within tumor area and reduci... |
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| Keywords: | hepatic carcinoma interventional therapy pharmacokinetics |
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