| 红霉素缓释微囊的制备及其释药机理的研究 |
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| 引用本文： | 李凌冰,徐明瑜,李琇.红霉素缓释微囊的制备及其释药机理的研究[J].生物医学工程研究,1997(1). |
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| 作者姓名： | 李凌冰 徐明瑜 李琇 |
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| 作者单位： | 山东大学生物医学工程研究中心，山东大学生物医学工程研究中心，山东大学校医院内科 济南 250100，济南 250100，济南 250100 |
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| 摘 要： | 本文旨在探讨红霉素微囊的制备及体外缓释机理。以明胶等为囊材,用红霉素制成微囊,研究微囊的厚度及孔隙度对药物释放速率的影响。进行理论分析,与实验结果相符性较好。
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| 关 键 词： | 微囊 释放速率 囊壁厚度 孔隙度 |
STUDY ON PREPARATION AND IN VITRO RELEASE MECHANISM OF MICROCAPSULES OF ERYTHROMYCIN |
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| Li Lingbing Xu Mingyu Li Xiu.STUDY ON PREPARATION AND IN VITRO RELEASE MECHANISM OF MICROCAPSULES OF ERYTHROMYCIN[J].Journal Of Blomedical Englneerlng Research,1997(1). |
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| Authors: | Li Lingbing Xu Mingyu Li Xiu |
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| Abstract: | In this paper the microcapsules of erythromycin were prepared and the mechanism of release was researched. The experiments in this study show that the release rate of the microeapsules is a function of the thickness and porosity and tortuosity of the coating. The equation was established, which was verified by the experiments. |
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| Keywords: | Microcapsules Releasing rate Thickness of coating Porosity |
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