Foveal Serous Retinal Detachment in Juvenile Idiopathic Arthritis-associated Uveitis |
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| Authors: | Feng Liang Celine Terrada Ghislaine Ducos de Lahitte Pierre Quartier Phuc Lehoang Jennifer E. Thorne |
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| Affiliation: | 1. Department of Ophthalmology, University of Paris VI, Pitié-Salpêtrière Hospital, Paris, France,;2. Unit of Immuno-Hematology and Pediatric Rheumatology, Necker-Enfants Malades Hospital, Paris, France,;3. Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, and;4. Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, Maryland, USA |
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| Abstract: | Purpose: In juvenile idiopathic arthritis (JIA)-associated uveitis complicated by foveal serous retinal detachment (FSRD), we documented the relationship between best corrected visual acuity (BCVA), level of anterior chamber flare and OCT features.Methods: Nine children (15 eyes) with FSRD were identified among 38 children with JIA-associated maculopathy. Outcome measures included BCVA, ocular inflammatory activity quantified by laser flare photometry and the macular profile analyzed by OCT.Results: The diagnosis of FSRD led to intensification of the treatment using subtenon’s injection of triamcinolone or systemic immunomodulatory therapy. The improvement of BCVA at presentation (0.46 logMAR) was significant at 36 months follow-up (0.15 logMAR). The resolution of FSRD along with visual improvement (p?=?0.0032) correlated with improvement in anterior chamber flare (p?=?0.01).Conclusion: FSRD is a complication of chronic JIA-associated uveitis that responds well to intensification of immunomodulation. Visual improvement is correlated with FSRD resolution and with flare photometry values. |
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| Keywords: | Flare foveal serous retinal detachment juvenile idiopathic arthritis OCT uveitis |
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