Low antimullerian hormone levels may be associated with cardiovascular risk markers in women with diminished ovarian reserve |
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| Authors: | Fatma Ferda Verit Hurkan Akyol Mehmet Nafi Sakar |
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| Affiliation: | 1. Department of Obstetrics &2. Gynecology, Suleymaniye Maternity, Research &3. Training Hospital, Infertility Research &4. Treatment Center, Istanbul, Turkey and;5. Gynecology, Diyarbakir Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey |
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| Abstract: | There is growing evidence that diminished ovarian reserve (DOR) may be associated with cardiovascular disease (CVD). The aim of the study was to investigate whether there was any relationship between antimullerian hormone (AMH) and CVD risk markers in the study.Ninety women with DOR and 90 women with normal ovarian reserve (NOR) attending the infertility unit at XXXX, were enrolled in the study. CVD risk markers such as insulin resistance [defined by the homeostasis model assessment ratio (HOMA-IR)], C-reactive protein (CRP), low density lipoprotein (LDL), high-density lipoprotein (HDL), total cholesterol (TC), and triglyceride (TG) were assessed. HOMA-IR, CRP, TG, LDL levels were higher and HDL and AMH were lower among patients with DOR compared with controls (p?p?There was a close relationship between low AMH and CVD risk markers in the study. Further studies with larger groups are needed to investigate the nature of this link in these patients. |
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| Keywords: | Antimullerian hormone cardiovascular risk C-reactive protein diminished ovarian reserve dyslipidemia insulin resistance |
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