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A trauma‐related survival predictive model of acute respiratory distress syndrome
Authors:Rui Tang  Hanghang Wang  Junnan Peng  Daoxin Wang
Institution:1. Department of Respiratory Medicine, Second Affiliated Hospital of Chongqing Medical University, Chongqing China
Abstract:PurposeThe purpose of this study was to construct and validate a simple model for the prediction of survival in patients with trauma‐related ARDS.MethodsThis is a single‐center, retrospective cohort study using MIMIC‐III Clinical Database.Results842 patients were included in this study. 175 (20.8%) died in‐hospital, whereas 215 (25.5%) died within 90 days. The deceased group had higher Acute Physiology Score (APS III), Sequential Organ Failure Assessment (SOFA), and Simplified Acute Physiology Score II (SAPS II). In multivariate logistic regression model, independent risk factors for mortality in ARDS patients included age (odds ratio] OR, 1.035; 95% confidence interval CI], 1.020–1.049), body mass index (OR, 0.957; 95% CI, 0.926–0.989), red blood cell distribution width (OR, 1.283; 95% CI, 1.141–1.443), hematocrit (OR, 1.055; 95% CI, 1.017–1.095), lactate (OR, 1.226; 95% CI, 1.127–1.334), blood urea nitrogen (OR, 1.025; 95% CI, 1.007–1.044), acute kidney failure (OR, 1.875; 95% CI, 1.188–2.959), sepsis (OR, 1.917; 95% CI, 1.165–3.153), type of admission (emergency vs. elective OR, 2.822; 95% CI, 1.647–4.837], and urgent vs. elective OR, 5.156; 95% CI, 1.896–14.027]). The area under the curve (AUC) of the model was 0.826, which was superior than the SAPS II (0.776), APS III (0.718), and SOFA (0.692). In the cross‐validation model, the accuracy of the test set was 0.823, the precision was 0.643, and the AUC was 0.813.ConclusionsWe established a prediction model using data commonly used in the clinic, which has high accuracy and precision and is worthy of use in clinical practice.
Keywords:acute respiratory distress syndrome  laboratory Inspection  predictive model  trauma
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