血清一氧化氮、一氧化氮合酶与彩色多普勒超声在卵巢癌诊断中的价值

目的 :探讨血清一氧化氮 (NO)、一氧化氮合酶 (NOS)及经阴道、经腹彩色多普勒超声联合应用对早期诊断卵巢癌的价值。方法 :对 97例卵巢肿瘤患者术前抽取空腹静脉血测定血清NO、NOS含量 ,经阴经腹彩色多普勒超声检查肿瘤特性 ,并与术后病理结果对比分析。结果 :恶性肿瘤患者血中NO、NOS含量高于良性肿瘤 (P <0 .0 1) ;彩色多普勒超声检查评分高于良性肿瘤 (≥ 3) ,差异显著 (P <0 .0 1) ;恶性肿瘤内部易显示血流信号 ,RI≤ 0 .5 ,与良性肿瘤差异显著 (P<0 0 1)。结论 :血清一氧化氮、一氧化氮合酶及彩色多普勒超声检查联合应用可大大提高卵巢良恶性肿瘤的诊断符合率 ,有助于早期卵巢癌的发现。

The value of serum NO,NOS levels and color Doppler ultrasonographic measurements used combinatively in differentiating malignant early ovarian neoplasms from benign masses

Objective:To evaluate the predictive value of serum NO,NOS levels and trtansvaginal,abdominal color Doppler ultrasonographic measurements used combinatively in differentiating malignant early ovarian neoplasms from benign masses.Methods:A total of 97 cases with ovarian masses were included in this study. Before operation, these patients underwent measurements of serum NO,NOS and transvaginal,abdominal color Doppler ultrasonographic measurements. We evaluate the significance of the combinative utility of the above measurements methods by contrasting with the pathologic reports.Results:Compared with the patients with benign masses, the malignant cases have notable differenation in serum NO,NOS levels, transvaginal and abdominal color Doppler ultrasonographic measurements grade.Conclusion:The combinative utility of serum NO,NOS,transvaginal and abdominal Doppler ultrosonography showed higher value in differentiating malignant early ovarian neoplasms from benign masses, and may be an effective diagnosis method.