| 杏仁核微量注射cAMP和ATP对大鼠睡眠和觉醒的影响 |
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| 引用本文： | 施蕾,徐颖.杏仁核微量注射cAMP和ATP对大鼠睡眠和觉醒的影响[J].蚌埠医学院学报,1998,23(4):217-218. |
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| 作者姓名： | 施蕾 徐颖 |
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| 作者单位： | [1]安徽中医学院生理学教研室 [2]寄生虫学教研室 |
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| 摘 要： | 目的：观察杏仁核内微量注射环磷酸腺苷和腺苷三磷酸（ＡＴＰ）的睡眠和觉醒的影响。方法：多导睡眠描记。结果：ｃＡＭＰ可减少觉醒（Ｗ），缩短入睡潜伏期（ＳＷＳ１），增加慢波睡眠（ＳＷＳ）和总睡眠时间（ＴＳＴ）；ＡＴＰ对睡眠无显著影响。结果：外源性ｃＡＭＰ可促进睡眠，抑制觉醒，杏仁核是睡眠－觉醒周期调节的重要部位。
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| 关 键 词： | 睡眠 杏仁核 环磷酸腺苷 腺苷三磷酸 觉醒 |
Effects of cAMP and ATP injection into amygdaloid nucleus on sleep and wakefulness in rats |
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| Shi Lei,Zhao Lezhang,Zhong Mingkui,Xu Ying,Huang Ying,Zhu Guoqing,Zhang Jingxing.Effects of cAMP and ATP injection into amygdaloid nucleus on sleep and wakefulness in rats[J].Journal of Bengbu Medical College,1998,23(4):217-218. |
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| Authors: | Shi Lei Zhao Lezhang Zhong Mingkui Xu Ying Huang Ying Zhu Guoqing Zhang Jingxing |
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| Abstract: | Objective:To invesgate the effects of cAMP and ATP microinjection into amygdaloid nucleus on sleep and wakefulness(W) in rats.Methods:The experiment was performed under polysomnography(PSG).Results:cAMP decreased W and latency of SWS 1,increased slow wave sleep(SWS) and total sleep time(TST),but didnot change paradoxical sleep(PS).ATP failed to induce any significant change in sleep and W.Conclusions:cAMP is effective in sleep promoting and wakefulness inhibiting in amygdaloid nucleus.Amygdaloid nucleus played an important role in regulating sleep and wakefulness. |
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| Keywords: | sleep amygdaloid lody adenosine cyclic monophosphate(cAMP) adenosine triphosphate(ATP) |
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