| 菊花莲子植物固体饮料流化床制粒工艺研究 |
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| 引用本文： | 龙敏玲,汪涛,陈理,向飞军.菊花莲子植物固体饮料流化床制粒工艺研究[J].中国医药导报,2013,10(9):105-108. |
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| 作者姓名： | 龙敏玲 汪涛 陈理 向飞军 |
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| 作者单位： | 龙敏玲(广东康美药物研究院股份有限公司,广东广州,510006)；汪涛(广东康美药物研究院股份有限公司,广东广州,510006)；陈理(广东康美药物研究院股份有限公司,广东广州,510006)；向飞军(广东康美药物研究院股份有限公司,广东广州,510006)； |
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| 摘 要： | 目的优化一步制粒工艺以制备菊花莲子固体饮料。方法对方中中药水煎提取、浓缩得到一定密度的流浸膏，以目测流化床中颗粒的流动性为考察指标，通过单因素和正交试验，考察辅料种类、添加量、物料温度、供液转速对制粒工艺的影响。结果最佳的工艺条件为供液转速5r／min，物料温度45℃，异麦芽酮糖醇添加量为流浸膏固形物的35％，辅料为麦芽糊精：白砂糖粉（2：1）。结论按优选的处方和工艺制得的固体饮料，含糖量低，流动性较好，工艺稳定。
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| 关 键 词： | 固体饮料 异麦芽酮糖醇 流动性 流化床制粒 |
Research for fluidized bed granulation technology of Chrysanthemum and Lotus Plant Beverage Solids |
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| LONG Minling,WANG Tao,CHEN Li,XIANG Feijun.Research for fluidized bed granulation technology of Chrysanthemum and Lotus Plant Beverage Solids[J].China Medical Herald,2013,10(9):105-108. |
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| Authors: | LONG Minling WANG Tao CHEN Li XIANG Feijun |
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| Institution: | Guangdong Kangmei Pharmaceutical Research Institute Co.,Ltd., Guangdong Province, Guangzhou 510006, China |
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| Abstract: | Objective To optimize the one step granulation preparation method of Chrysanthemum and Lotus Plant Beverage Solids. Methods The liquidity was used as indexes, the type and dosage of excipient, material temperature, liquid velocity were investigated by the single factor and orthogonal experiment of a certain density of liquid extract. Results The optimal process conditions： liquid velocity was 5 r/min, temperature was 45℃, the dosage of isomalt was 35% of dry solids, excipient was malt dextrin：white sugar powder （2：1）. Conclusion This technique is reasonable and feasible. The product has low sugar content, good fluidity and process stability. |
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| Keywords: | Solid beverage Isomalt Flow Fluidized bed granulation |
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