| 沙利度胺的临床新应用与不良反应研究概述 |
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| 引用本文： | 裴丽,罗艳,黄显金,王丽伟,刘京伟.沙利度胺的临床新应用与不良反应研究概述[J].中国药师,2016(5):977-980. |
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| 作者姓名： | 裴丽 罗艳 黄显金 王丽伟 刘京伟 |
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| 作者单位： | 解放军总医院第一附属医院药剂药理科 北京 100048 |
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| 摘 要： | 摘 要 目的：分析沙利度胺的不良反应（ADRs）和临床应用，为临床合理用药提供参考。方法: 系统回顾国外有关沙利度胺的临床文献报道，并进行分析整理。结果: 沙利度胺的不良反应涉及胃肠道反应、血液毒性、心血管毒性、神经毒性、皮肤损害、肺栓塞等。此外，其新的临床应用也较为广泛。结论:临床医师及药师应重视沙利度胺的用药风险与合理用药，以保障临床用药安全、有效。
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| 关 键 词： | 沙利度胺 临床新应用 药品不良反应 合理用药 |
| 收稿时间： | 2015/11/30 0:00:00 |
| 修稿时间： | 1/2/2016 12:00:00 AM |
New Clinical Application and Adverse Reactions of Thalidomide |
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| Pei Li,Luo Yan,Huang Xianjin,Wang Liwei,Liu Jingwei.New Clinical Application and Adverse Reactions of Thalidomide[J].China Pharmacist,2016(5):977-980. |
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| Authors: | Pei Li Luo Yan Huang Xianjin Wang Liwei Liu Jingwei |
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| Institution: | Department of Pharmacy, the First Affiliated Hospital of PLA General Hospital, Beijing 100048, China |
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| Abstract: | ABSTRACT Objective: To analyze the adverse drug reactions (ADR) and clinical application of thalidomide to provide useful reference for rational medication in clinics. Methods: The case reports and literatures from foreign countries on the clinical medication of thalidomide were analyzed and summarized. Results: The ADR of thalidomide included gastrointestinal reaction, hematotoxicity, cadiovascular toxicity, neurotoxicity, skin lesion, pulmonary embolism and so on. Its new medication methods were widely used in clinics. Conclusion:Clinicians and pharmacists should pay more attention to the medication risks and rational use of thalidomide in order to assure the safety and effectiveness of clinical drug use. |
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| Keywords: | Thalidomide New clinical application ADR Rational medication |
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