| 男性非淋菌性尿道炎患者支原体对抗菌药物的敏感性 |
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| 引用本文： | 钱悦,褚淑娟,曾甫清,陈思远,吴艳,陈善娟,涂亚庭.男性非淋菌性尿道炎患者支原体对抗菌药物的敏感性[J].临床泌尿外科杂志,2006,21(7):508-510. |
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| 作者姓名： | 钱悦 褚淑娟 曾甫清 陈思远 吴艳 陈善娟 涂亚庭 |
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| 作者单位： | 华中科技大学同济医学院附属协和医院皮肤科,武汉,430022;华中科技大学同济医学院附属协和医院麻醉科;华中科技大学同济医学院附属协和医院泌尿外科 |
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| 摘 要： | 目的:了解支原体在男性非淋菌性尿道炎(NGU)的作用和体外对药物敏感性。方法:对864例疑为NGU的男性患者泌尿生殖道标本进行了支原体型别鉴定,用微量肉汤稀释法对支原体进行9种抗菌药物的敏感性测定。结果:272例(31.4%)支原体培养阳性,其中解脲支原体(Uu)176例,人型支原体(Mh)9例;Uu Mh混合感染87例。97.2%的支原体对9种抗菌药物有不同程度的耐药。Uu Mh混合感染的耐药率明显高于单纯Uu感染。结论:Uu Mh混合感染耐药性升高并发生耐药谱变化。对支原体的定期耐药性监测,对临床用药有重要指导意义。
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| 关 键 词： | 支原体 药物敏感性 抗菌药物 |
| 文章编号： | 1001-1420(2006)07-0508-03 |
| 收稿时间： | 02 9 2006 12:00AM |
| 修稿时间： | 2006年2月9日 |
Mycoplasma detection in male patients with non-gonococcal urethritis and study of their susceptibility to 9 antimicrobial agents |
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| QIAN Yue,CHU Shujuan,ZENG Fuqing,CHEN Siyuan,WU Yan,CHEN Shangjuan,TU Yating.Mycoplasma detection in male patients with non-gonococcal urethritis and study of their susceptibility to 9 antimicrobial agents[J].Journal of Clinical Urology,2006,21(7):508-510. |
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| Authors: | QIAN Yue CHU Shujuan ZENG Fuqing CHEN Siyuan WU Yan CHEN Shangjuan TU Yating |
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| Institution: | 1.Department of Dermatology, Union Hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan, 430022, China; 2 Department of Anesthesiology, Union Hospital, Tongji medical college, Huazhong University of Science and Technology;3 Department of Urology, Union Hospital, Tongji medical college, Huazhong University of Science and Technology |
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| Abstract: | Objective:To explore the pathogenesis of Ureaplasma urealyticum(Uu) and Mycoplasma homimis(Mh) in male non-gonococcal urethritis(NGU) and their susceptibility to 9 antimicrobial agents.Methods:The susceptibility in vitro to 9 antimicrobial agents was determined by microdilution method.Results:In 864 male patients suspected with NGU,272 were positive for mycoplasma culture.Among them,176 cases Mh infection,87 cases having both Uu and Mh infection.The total drug resistance rate for mycoplasma was about 97.2%.The total drug resistance rate for Uu Mh mixed infection group was significantly higher than that of Uu infection group.Conclusions:It was suggested that monitoring the varrance of resistance of mycoplasma was important for directing drug use in clinical practice.Uu Mh mixed infection showed an increased drug resistance and changes of drug resistance spectrum. |
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| Keywords: | Ureaplasma urealyticum Mycoplasma hominis Drug susceptibility Antimicrobial agent |
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