晚睡影响心血管疾病风险因素的相关性研究进展 |
| |
作者姓名: | 张蕊 康毅敏 |
| |
作者单位: | 内蒙古医科大学内蒙古自治区分子病理学重点实验室,内蒙古医科大学内蒙古自治区分子病理学重点实验室 |
| |
基金项目: | 内蒙古自然科学基金面上项目(2022MS08068) |
| |
摘 要: | 心血管疾病(cardiovascular disease,CVD)是导致全球死亡率升高的最大单一因素,其被列为全球重大健康问题。其中载脂蛋白A-I(Apolipoprotein A-I,apo A-I)、载脂蛋白B(Apoprotein B,Apo B)以及Apo B/Apo A-I是CVD的有效预测指标。 在引起CVD的众多原因中,就寝时间是不容忽视的风险因素,长期晚睡易引发失眠、昼夜节律紊乱等一系列睡眠问题,进而通过影响神经递质水平、引发全身慢性炎症反应、影响脂肪酸代谢和血压调节等机制最终促使CVD的发生和发展。因此养成规律、健康的就寝时间对预防CVD至关重要。
|
关 键 词: | 晚睡 心血管疾病 炎症 神经递质 脂肪酸 |
收稿时间: | 2023/4/22 0:00:00 |
修稿时间: | 2023/5/9 0:00:00 |
RESEARCH PROGRESS ON THE CORRELATION BETWEEN LATE BEDTIME AND CARDIOVASCULAR DISEASE RISK FACTORS |
| |
Authors: | Zhang Rui and Kang Yimin |
| |
Institution: | Inner Mongolia Key Laboratory of Molecular Pathology,Inner Mongolia Medical University |
| |
Abstract: | Cardiovascular disease (CVD) is the most crucial factor in increasing global mortality, a significant global health problem. Apolipoprotein A-I (apo A-I), Apolipoprotein B (Apo B), and Apo B/Apo A-I were effective predictors of CVD. Among the many causes of CVD, bedtime is a risk factor that cannot be ignored. Long-term late bedtime causes insomnia, circadian rhythm disturbance, and a series of sleep problems, which ultimately promote the occurrence and development of CVD by affecting the level of neurotransmitters, triggering a systemic chronic inflammatory response, affecting fatty acid metabolism and blood pressure regulation, and other mechanisms. Therefore, developing a regular and healthy bedtime is crucial to preventing CVD. This review comprehensively analyzes the pathophysiological mechanism of late bedtime-mediated cardiovascular diseases, such as neurotransmitters and inflammatory factors, which can guide sleep hygiene to prevent the occurrence of cardiovascular diseases. |
| |
Keywords: | Late bedtime Cardiovascular diseases Inflammation Neurotransmitter Fatty acid |
|
| 点击此处可从《》浏览原始摘要信息 |
| 点击此处可从《》下载免费的PDF全文 |
|