经颅磁刺激联合乌灵胶囊对慢性耳鸣患者睡眠质量和情绪状态的影响

<正>对于慢性耳鸣，临床多在消除病因基础上给予药物或物理治疗，其中经颅磁刺激是最常见的物理疗法之一，通过电容器产生的脉冲电流作用于人体大脑皮层的中枢神经，使神经细胞产生兴奋或者抑制，继而改善耳鸣^1-2]。但据相关调查指出，经颅磁刺激只能短暂改善耳鸣症状，对患者睡眠、精神焦虑等改善不佳^3-4]。乌灵胶囊主要由乌灵菌组成，具有健脑补肾、养心安神功效，常被用来缓解因心肾亏虚而引起的失眠、心悸、神经衰弱等症状，临床上也将其用于治疗耳鸣。

The effect of transcranial magnetic stimulation combined with Wuling capsule on sleep quality and emotional state in patients with chronic tinnitus

Objective Explore the effect of transcranial magnetic stimulation combined with Wuling capsules on sleep quality and emotional state in patients with chronic tinnitus. Methods A total of 132 patients with chronic tinnitus who visited the hospital from February 2022 to February 2023 were selected as the research objects. They were randomly divided into three groups according to the random number table, with 44 in each group. Group A patients were treated with Wuling capsule; Patients in group B were treated with low frequency repetitive transcranial magnetic stimulation; Group C patients were treated with Wuling capsule combined with transcranial magnetic stimulation. The therapeutic effect, tinnitus improvement, tinnitus severity, sleep quality, emotional state and adverse reaction rate of the three groups of patients were recorded to compare the clinical effects of the three methods in treating chronic tinnitus patients. Results The total effective rate of group C was significantly higher than that of groups A and B (P<0.05); After treatment, the scores of VAS and THI in the three groups decreased significantly, and the scores in group C decreased more significantly than those in groups A and B (P<0.05); After treatment, the number of Grade V patients in the three groups decreased, and the number of Grade I-II patients became more, and the number of Grade I-II patients in Group C was significantly higher than that in Groups A and B (P<0.05); After treatment, the sleep quality and emotional state of the three groups were improved, and the sleep quality and emotional state of group C were improved more significantly than those of groups A and B (P<0.05); There was no significant difference in the incidence of adverse reactions among the three groups during treatment (P>0.05). Conclusion Wuling capsule combined with transcranial magnetic stimulation can significantly improve the sleep quality and emotional state of patients with chronic tinnitus, reduce the severity of tinnitus, and alleviate the discomfort of tinnitus.