| 壳聚糖-水杨酸、壳聚糖银的合成及抑菌活性研究 |
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| 引用本文： | 许闽,崔永霞,吴明侠. 壳聚糖-水杨酸、壳聚糖银的合成及抑菌活性研究[J]. 中国现代药物应用, 2010, 4(21): 18-19 |
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| 作者姓名： | 许闽 崔永霞 吴明侠 |
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| 作者单位： | 河南中医学院,450008 |
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| 摘 要： | 目的研究壳聚糖-水杨酸与壳聚糖银的合成方法及对金黄色葡萄球菌、铜绿假单胞菌的抑菌作用。方法用稀释法和凹环法对烧伤常见的病原菌进行抑菌实验。结果壳聚糖银表现出较好的抑菌效果,而壳聚糖-水杨酸抑菌效果次之。结论能为壳聚糖衍生物在临床烧伤感染用药提供科学依据。
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| 关 键 词： | 壳聚糖 抑菌作用 金黄色葡萄球菌 铜绿假单胞菌 |
Synthesis of salicylic chitosan, silver chitosan and the experimental study on their bacteriostasis |
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| XU Min,CUI Yong-xia,WU Ming-xia. Synthesis of salicylic chitosan, silver chitosan and the experimental study on their bacteriostasis[J]. Chinese Journal of Modern Drug Application, 2010, 4(21): 18-19 |
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| Authors: | XU Min CUI Yong-xia WU Ming-xia |
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| Affiliation: | . Henan College of TCM,Henan 450008,China |
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| Abstract: | Objective To develope a synthesis method of salicylic chitosan and silver chitosan,then to study their bacteriostasis to staphylococcus aureus （ S . aureus） and pseudomonas aeruginosa （ P. aeruginosa） . Methods Dilution and concavering was used to study the bacteriostasis to some ordinary bacteria which cause infection in burn. Results Salicylic chitosan showed better bacteriostatic effect than salicylic chitosan. Conclusion The study can provide scientific basis for chitosan derivates is used in clinical application. |
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| Keywords: | Chitosan Bacteriostasis Staphylococcus aureus Pseudomonas aeruginosa |
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