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Psychosis and epilepsy in young people
Institution:1. South London and Maudsley NHS Trust, Belgrave Department of Child Psychiatry, King''s College Hospital, London, UK;2. Institute of Psychiatry, Maudsley Hospital, London, UK;1. Departments of Pediatrics;2. Internal Medicine and;3. Collaboration for Organ Perfusion, Protection, Engineering and Regeneration Laboratory, The Ohio State University;4. Section of Pulmonary Medicine, Nationwide Children’s Hospital;5. Department of Surgery, The Ohio State University;6. Department of Cardiovascular Perfusion, Nationwide Children’s Hospital;7. Department of Anesthesiology, The Ohio State University;8. Department of Anesthesiology & Pain Medicine, Nationwide Children’s Hospital, Columbus, Ohio;1. Laboratory of Veterinary Pathology, Tokyo University of Agriculture and Technology, 3-5-8 Saiwai-cho, Fuchu-shi, Tokyo 183-8509, Japan;2. Pathogenetic Veterinary Science, United Graduate School of Veterinary Sciences, Gifu University, 1-1 Yanagido, Gifu-shi, Gifu 501-1193, Japan;1. Department of Respiratory Medicine, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi‘an, China;2. Department of Pediatrics, BaYi Children''s Hospital of the PLA Army General Hospital, Beijing, China;3. The Clinical Medical College of the PLA Army, Second Military Medical University of People''s Liberation Army, Shanghai, China;4. Department of Respiratory Medicine, The First Affiliated Hospital of Xi’an Jiaotong University, Xi‘an, China;5. Department of Respiratory Medicine, Shaanxi Provincial People''s Hospital, Xi‘an, China;1. Department of Interventional Radiology, Pomeranian Medical University, Neurointerventional Cath Lab MSW Hospital, Rybacka 1, 70204 Szczecin, Poland;2. Department of Diagnostic Imaging and Interventional Radiology, Pomeranian Medical University, Rybacka 1, 70204 Szczecin, Poland;3. Euromedic Lowersilesian Medical Center, Interventional Neuroradiology CathLab, Traugutta 116, 50420 Wrocław, Poland;4. Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Rybacka 1, 70204 Szczecin, Poland
Abstract:The aim of this study was to describe the clinical characteristics of children and young people under 19 with both epilepsy and a psychotic state (schizophrenia-like psychotic episode, organic delusional disorder, or other brief psychotic episode). In total, the clinical case notes for 17 young people with these characteristics were identified retrospectively from three different sources. Compared with a group of young people with psychosis without epilepsy, children with epilepsy and psychosis more frequently had other neuropsychological problems like learning disability and autism. Both groups had a high rate of family histories of mental illness and social disability. Contrary to the findings in adults with psychosis and epilepsy, in this group of young people, psychosis was associated neither with temporal lobe epilepsy nor with mesial temporal sclerosis. The children with psychosis and epilepsy had a variety of seizure types and structural abnormalities.
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