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Sebaceous carcinoma in association with actinic keratosis: A report of two cases with an immunohistochemical study
Authors:Noriyuki Misago  Maki Kuwashiro  Noriko Tsuruta  Yutaka Narisawa
Affiliation:Division of Dermatology, Department of Internal Medicine, Faculty of Medicine, Saga University, Saga, Japan
Abstract:We report two cases of sebaceous carcinoma associated with actinic keratosis (AK) with an immunohistochemical study, which suggests the possibility that sebaceous carcinoma really does develop within AK. Case 1 had sebaceous carcinoma arising within the atrophic type AK and case 2 had sebaceous carcinoma associated with bowenoid AK in the periphery and some parts of the overlying epidermis of the lesion.
Keywords:adipophilin  atrophic type actinic keratosis  bowenoid type actinic keratosis  cytokeratin 1  sebaceous carcinoma
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