0.125%罗哌卡因复合芬太尼用于分娩镇痛的临床观察

目的研究0.125%罗哌卡因辅以小剂量芬太尼采用硬膜外阻滞方式进行分娩镇痛的临床效果。方法选择40例自愿要求分娩镇痛的ASAⅠ~Ⅱ足月初产妇为镇痛组,宫口开2~3 cm时经硬膜外穿刺置管,首次注入0.125%罗哌卡因与1μg/mL芬太尼混合液5~10 mL,以后可根据镇痛效果和产程进展间断追加。记录两组产妇疼痛情况、运动神经阻滞情况、产程、分娩方式、产后出血及新生儿Apgar评分。结果镇痛组产妇疼痛明显减轻,无运动神经阻滞、能降低剖宫产率,而对产妇、新生儿无影响。结论0.125%罗哌卡因辅以小剂量芬太尼进行分娩镇痛,安全有效、是比较理想的"可行走的硬膜外镇痛"方法之一,值得临床推广。

The clinical investigation of epidural labor analgesia by 0.125% ropivacaine combined with fentanyl

Objective To examine the efficacy of 0.125% ropivacaine combined with fentanyl on labor pain relief.Methods 40 ASA Ⅰ～Ⅱ full-term primiparas who requested epidural analgesia were chose.When the cervical dilation was about 2～3 cm,they received 5～10 mL mixed liquor of 0.125% ropivacaine and 1 μg/mL fentanyl,then they were intermittently given a boost according to the analgesia effect and the progress of labor.The pain score,motor nerve block score,birth process,labor way,postpartum hemorrhage and newborn Apgar score of the two groups were recorded.Results The epidural analgesia had no significant effect on vital signs of the parturients and newborns.The pain was significantly relieved with no motor nerve block and low rate of cesarean section.Conclusion 0.125% ropivacaine combined with low dose of fentanyl is an ideal "ambulatory epidural analgesia" method.