我院100例药品不良反应报告分析

目的分析我院药品不良反应（ADR）发生的特点及其规律，确保临床用药的合理、安全。方法采用回顾性方法，对我院2007—2008年报的100份ADR报告，按患者年龄、性别、给药途径、引起ADR的药品种类、涉及器官或系统以及临床表现等进行统计、分析。结果静脉给药较其他给药途径更易发生ADR（占68．0％）；抗感染药物引发ADR的比例最高（占51．0％），其次为神经系统与心血管系统药物。结论加强ADR监控意识，并完善相关报告分析制度，以确保临床用药的安全、有效。

ADR reports:analysis of 100 cases in our hospital

Objective To analyze the characteristics and regularity of the adverse drug reaction （ADR） occurred in our hospital so as to ensure rational drug use and clinical safe. Methods By a retrospective study,a total of 100 ADR case reports collected from our hospital from 2007 to 2008 were subjected to a statistical analysis in respect of patients＇ age and sex,route of administration,drug categories inducing ADRs, the organs or system involved and the clinical manifestations etc. Results Of the total 100 ADR cases ,68.0 % were induced by intravenous administration, and 51.0 % were induced by anti-infective drugs, followed by drugs used for nervous system and cardiovascular disease. Conclusion ADR monitoring should be strengthened and the related ADR reporting and analyzing system should be evolved to ensure clinical safe and effective use of drugs.