首页 | 本学科首页   官方微博 | 高级检索  
检索        


Specificity and sensitivity of esophageal motor abnormality in systemic sclerosis (scleroderma) and related diseases: A cineradiographic study
Authors:William L Campbell  Joseph C Schultz
Institution:(1) Department of Radiology, Presbyterian-University Hospital, University Health Center of Pittsburgh, Pittsburgh, Pennsylvania, USA
Abstract:Using cineradiography, we studied esophageal peristalsis in patients with suspected systemic sclerosis and related diseases, and in patients without known esophageal disease who had been referred for upper gastrointestinal series. Patterns of peristaltic abnormality were identified, and specificity and sensitivity values calculated. Esophageal aperistalsis was 100% specific, and consistently weak peristalsis after all, swallows was 88% specific for systemic sclerosis. Specificity decreased to 70% in patients over age 60. Abnormal peristalsis after some, but not all, swallows had only 52% specificity. Consistently abnormal peristalsis (absent or diminished) was 67% sensitive for scleroderma. Although a high sensitivity value (87%) for cineradiography can be obtained by considering any peristaltic abnormality as a sign of scleroderma, this is achieved at the price of an undesirably high number of false positives (specificity 40%).
Keywords:Esophagus  motility  Scleroderma  radiologic diagnosis  Cineradiography  indications
本文献已被 SpringerLink 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号