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KV级CBCT图像引导胸部肿瘤治疗中三种配准方式的比较
引用本文:曾凡艳,朱小东,曲颂,李龄,付庆国,陈龙,梁世雄. KV级CBCT图像引导胸部肿瘤治疗中三种配准方式的比较[J]. 现代肿瘤医学, 2014, 0(8): 1910-1913. DOI: 10.3969/j.issn.1672-4992.2014.08.51
作者姓名:曾凡艳  朱小东  曲颂  李龄  付庆国  陈龙  梁世雄
作者单位:广西医科大学附属肿瘤医院放疗科,广西 南宁 530021
基金项目:广西研究生教育创新计划(编号:2010105981002D30);广西卫生厅自筹经费科研课题(编号:Z2011207)
摘    要:目的:探讨胸部肿瘤IGRT治疗中不同图像配准方法对摆位误差的影响。方法:医科达Synergy IGRT直线加速器分别治疗胸部肿瘤患者20例,每次治疗前均行CBCT扫描,重建获得的CBCT图像与原计划CT图像进行配准,分析X、Y、Z轴方向的平移误差及旋转误差,比较骨性配准、灰度值配准及手动配准间的差异。结果:20例胸部肿瘤患者治疗前共行384次CBCT扫描。手动配准、骨性配准、灰度值配准在X轴的平移误差分别为(0.01±0.29)cm、(0.04±0.31)cm、(-0.02±0.28)cm,在Y轴的平移误差分别为(0.11±0.41)cm、(0.12±0.45)cm、(0.09±0.41)cm,在Z轴的平移误差分别为(-0.11±0.23)cm、(-0.05±0.22)cm、(-0.08±0.23)cm;X轴的旋转误差分别为(0.61±1.09)°、(0.34±1.44)°、(0.66±1.28)°,在Y轴的旋转误差分别为(0.06±0.83)°、(0.04±1.89)°、(0.16±1.6)°,在Z轴的旋转误差分别为(-0.17±1.45)°、(-0.19±1.53)°、(-0.13±1.45)°。结果显示手动配准、骨性配准和灰度值配准三种方式之间存在明显的差异。结论:胸部肿瘤患者行IGRT时,需要根据病变具体部位选择配准方式,建议自动配准后必要时结合手动微调,直到配准结果符合要求。

关 键 词:锥形束CT  配准方式  胸部肿瘤

The set - up errors with different image alignment for thoracic tumor underwent image guided radiation therapy
Zeng Fanyan,Zhu Xiaodong,Qu Song,Li Ling,Fu Qingguo,Chen Long,Liang Shixiong. The set - up errors with different image alignment for thoracic tumor underwent image guided radiation therapy[J]. Journal of Modern Oncology, 2014, 0(8): 1910-1913. DOI: 10.3969/j.issn.1672-4992.2014.08.51
Authors:Zeng Fanyan  Zhu Xiaodong  Qu Song  Li Ling  Fu Qingguo  Chen Long  Liang Shixiong
Affiliation:Department of Radiotherapy,Cancer Hospital of Guangxi Medical University,Guangxi Nanning 530021,China.
Abstract:To investigate the optimal alignment methods for the treatment of thoracic tumor in IGRT. Methods:All 20 thoracic tumor patients were treated with the Elekta Synergy IGRT system. KV - CBCT images re-ceived before every treatment fraction. The difference in bone alignment,grey value alignment and manual alignment was compared. Results:Total of 384 sets of CBCT images were analyzed for 20 thoracic tumor patients. The mean ± standard deviation in the X,Y and Z axis directions were(0. 01 ± 0. 29)cm,(0. 04 ± 0. 31)cm,( - 0. 02 ± 0. 28) cm;(0. 11 ± 0. 41)cm,(0. 12 ± 0. 45)cm,(0. 09 ± 0. 41)cm;( - 0. 11 ± 0. 23)cm,( - 0. 05 ± 0. 22)cm,( - 0. 08 ± 0. 23)cm in thoracic tumor with bone alignment,grey value alignment and manual alignment respectively. The mean ± standard deviation in the X,Y and Z rotation directions were(0. 61 ± 1. 09)°,(0. 34 ± 1. 44)°,(0. 66 ± 1. 28)°;(0. 06 ± 0. 83)°,(0. 04 ± 1. 89)°,(0. 16 ± 1. 6)°;( - 0. 17 ± 1. 45)°,( - 0. 19 ± 1. 53)°,( - 0. 13 ± 1. 45)° in thoracic tumor with bone alignment,grey value alignment and manual alignment respectively. There was significant difference among the three alignments. Conclusion:There exists some extent of setup error in 3DCRT or IMRT of tho-racic tumor patients. Alignment can be choiced based on the disease region. It is suggested that manul adjustment after automatic alignment is necessary.
Keywords:CBCT  alignment  thoracic tumor
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