| 血清胃癌相关抗原联合胸苷激酶检测在胃癌诊断中的临床价值 |
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| 引用本文： | 王云峰,;高美华,;宋晓锋.血清胃癌相关抗原联合胸苷激酶检测在胃癌诊断中的临床价值[J].现代肿瘤医学,2014(8):1883-1885. |
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| 作者姓名： | 王云峰 ;高美华 ;宋晓锋 |
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| 作者单位： | [1]青岛城阳区人民医院检验科,山东青岛266109; [2]青岛大学医学院免疫学教研室,山东青岛266000 |
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| 摘 要： | 目的：评价血清胃癌相关抗原（MG7- Ag）联合胸苷激酶（TK1）检测对胃癌患者的临床诊断价值。方法：选取2011年9月-2013年7月期间在青岛市城阳区人民医院就诊的胃病患者130例和健康查体者30例，分别检测 MG7- Ag 和 TK1在各受试者血清中的水平。结果：胃癌组血清 MG7- Ag 和 TK1含量及阳性检出率均明显高于健康对照组和胃良性病变组（P ﹤0.01），二者联合检测阳性率最高为75.0%。结论：血清MG7- Ag 和 TK1的联合检测对胃癌的诊断具有极高的临床价值。
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| 关 键 词： | 胃癌 血清胃癌相关抗原 胸苷激酶 |
Clinical significance of the combined detection of MG7 - Ag and TK1 in gastric cancer |
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| Institution: | Wang Yunfeng, Gao Meihua, Song Xiaofeng( 1 Chengyang District People＇s Hospital Laboratory, Shandong Qingdao 266109, China ;2 Immunology Office of Medical College, Qingdao University, Shandong Qingdao 266000, China.) |
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| Abstract: | To explore combined detection of the valae of the gastric cancer related antigen（MG7-Ag） and thymidine kinase（TK1）,gastric cancer diagnosis. Methods：All 130 gastric disease patients and 30 healthy sub-jects were detected for MG7-Agand TK1 in the serum. Results：The contents of serum are MG7-Ag and TK1 in gastric cancer group significantly higher than that in control group（P ﹤ 0. 01）;the positive rates of MG7-Ag and TK1 were significantly higher than that in control group（P﹤0. 01）. Combined detection,the positive rate was up to75. 0%. Conclusion：The combined detection of serum MG7-Ag and TK1 is of high clinical significance on diagno-sing gastric cancer. |
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| Keywords: | gastric cancer MG7 - Ag TK1 |
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