乳腺癌腋窝淋巴结转移的多因素分析

目的:研究乳腺癌腋窝淋巴结转移与年龄、民族、初潮年龄、第一胎生育年龄、绝经、绝经年龄、病程、哺乳时间、妊娠次数、肿瘤部位、肿瘤大小（B超、钼靶、MRI分别测值）、病理分型、雌激素受体（ER）、孕激素受体（PR）、C-erbB-2基因表达之间的关系及规律，为乳腺癌手术中腋窝淋巴结清扫术的指征提供理论依据。方法:回顾性分析356例乳腺癌患者的临床资料。结果:腋窝淋巴结转移228例（64%），无转移128例（36%）；腋窝淋巴结转移与第一胎生育年龄、妊娠次数、哺乳时间、病程、肿瘤大小(B超、钼靶、MRI)、肿瘤部位、病理类型相关（P<0.05），P值分别为0.007、0.005、0.006、0.022、（0.001、0.000、0.020）、0.009、0.000。结论:腋窝淋巴结的转移受多种因素影响。

Multiple factors analysis of axillary lymph node metastasis of breast cancer

To study the relation between metastasis of breast cancer and age,nationality,age of menar-che,the first child - bearing age,pausimenia,the age of menopause,the course of disease,numbers of pregnancies,the site of the tumor,tumor size（ultrasonic,mammography,MRI）,time of nursing,pathological type,ER,PR,the expres-sion of C - erbB - 2 gene. Methods：Make retrospective analysis for 365 cases of breast cancer patients who have been proved by pathology. Results：There were 228 metastases cases（64% ）in 365 cases and 128（36% ）cases haven＇t transfered. There were relationships（P ﹤ 0. 05）between axillary lymph node metastasis and the first child - bearing age,numbers of pregnancies,time of nursing,the course of disease,tumor size（ultrasonic,mammograph,MRI meas-ured value）,the site of the tumor,pathological type,P values were 0. 007,0. 005,0. 006,0. 022,（0. 001,0. 000, 0. 020）,0. 009,0. 000. Conclusion：Multiple factors influence axillary lymph node metastasis.