Telomeric (TTAGGG)n Sequences Are Associated With Nucleolus Organizer Regions (NORs) in the Wood Lemming

The distribution of the (TTAGGG)_n telomeric sequence was studied in chromosomes of the wood lemming, Myopus schisticolor, by fluorescence in-situ hybridization. As expected, the hybridization signals were observed at telomeres of all chromosomes. However, quite a number of interstitial telomeric sites were present in the pericentric heterochromatic regions. Consistent strong hybridization signals were also seen at one terminus of chromosomes 5, 7 and 12–15. By post-hybridization G-banding and silver-staining, the large blocks of the telomeric sequences on chromosomes 5 and 12 were localized to nucleolus organizer regions (NORs). This revised version was published online in August 2006 with corrections to the Cover Date.