单侧翼管神经切断术治疗变应性鼻炎的疗效及影响因素分析

目的探索单侧翼管神经切断术治疗变应性鼻炎（AR）的临床疗效，并分析影响疗效的相关因素。方法选取2013年1月—2017年1月山西医科大学第二医院收治的130例中-重度AR患者为研究对象，所有患者均于鼻内镜下行单侧翼管神经切断术，并收集相关资料，包括年龄、性别、病程、吸烟与否、有无尘螨及花粉过敏、有无鼻息肉及哮喘、视觉模拟量表评分 (VAS)。评估术后1年的临床治疗效果，同时采用Logistic回归法分析影响疗效的相关因素。结果130例AR患者有效率为75.38%（98/130），无效率为24.61%（32/130）；Logistic回归分析显示，合并鼻息肉是影响术后疗效的主要因素（P<0.05）。结论单侧翼管神经切断术治疗AR能够获得较好的临床效果，安全性好，合并鼻息肉是影响术后疗效的危险因素。

Analysis of curative effect and its influencing factors of unilateral vidian neurectomy in the treatment of patients with allergic rhinitis

ObjectiveTo investigate the clinical effect of unilateral vidian neurectomy on allergic rhinitis (AR) and to analyze the related factors that affecting the clinical effect.MethodsA total of 130 patients with severe AR admitted to the Second Hospital of Shanxi Medical University from January 2013 to January 2017 were selected as the study objects. All patients were treated with unilateral vidian neurectomy under nasal endoscopy, and the relevant data were collected, including age, gender, course of disease, smoking, dust mite allergy, pollen allergy, nasal polyps, asthma, Visual analogue scale(VAS). The clinical therapeutic effect was evaluated 1 year after operation. Meanwhile, the method of Logistic regression was used to analyze the influencing factors of clinical treatment effect.ResultsThe therapeutic efficiency of the 130 patients with AR was the effectiveness 75.38%(98/130), and the ineffectiveness 24.61%(32/130). Logistic regression analysis showed that nasal polyps were the main factors affecting postoperative efficacy (P<0.05).ConclusionsThe unilateral vidian neurectomy for the treatment of AR with better clinical efficacy and safety. However, allergic rhinitis with nasal polyps showed a poor prognosis.