| 脂联素在骨代谢中的研究进展 |
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| 引用本文： | 冯瑶,贾婷婷,王亚楠,张东姣,徐欣. 脂联素在骨代谢中的研究进展[J]. 口腔医学, 2021, 41(3): 284-288. DOI: 10.13591/j.cnki.kqyx.2021.03.018 |
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| 作者姓名： | 冯瑶 贾婷婷 王亚楠 张东姣 徐欣 |
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| 作者单位： | 1. 山东大学口腔医学院2. 山东大学口腔医院 |
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| 基金项目： | 泰山学者建设工程专项基金 |
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| 摘 要： | 脂联素是由脂肪组织分泌的一种内源性细胞因子,与受体结合后,参与机体的代谢调节.因此脂联素及脂联素受体也成为治疗代谢性疾病的重要分子靶标.脂联素信号传导的研究对指导临床上骨代谢相关疾病的治疗有着积极的作用.本文就脂联素的生物学特性及其信号传导、脂联素对骨代谢的影响作一综述,为脂联素在骨代谢疾病中的治疗提供参考.
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| 关 键 词： | 脂联素 脂联素受体 脂肪细胞因子 骨代谢 |
| 收稿时间： | 2020-05-27 |
Research progress of adiponectin in bone metabolism |
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| FENG Yao,JIA Tingting,WANG Yanan,ZHANG Dongjiao,XU Xin. Research progress of adiponectin in bone metabolism[J]. Stomatology, 2021, 41(3): 284-288. DOI: 10.13591/j.cnki.kqyx.2021.03.018 |
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| Authors: | FENG Yao JIA Tingting WANG Yanan ZHANG Dongjiao XU Xin |
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| Affiliation: | (Department of Implantology,School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University,Jinan 250012,China) |
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| Abstract: | Adiponectin(APN)is an endogenous cytokine secreted by adipose tissue.After binding to the receptor,it participates in the body’s metabolic regulation.Therefore,adiponectin and adiponectin receptors have become important molecular targets for the treatment of metabolic diseases.The research of adiponectin signal transduction has a positive effect on guiding the clinical treatment of bone metabolism related diseases.This article reviews the biological characteristics of adiponectin,its signal transduction,and the effects of adiponectin on bone metabolism to provide a reference for the treatment of adiponectin in bone metabolic diseases. |
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| Keywords: | adiponectin adiponectin receptor adipokine bone metabolism |
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