51例老年子宫内膜癌临床分析

目的 :分析老年子宫内膜癌的临床特点、病理类型及处理方法 ,以期进一步指导临床治疗。方法 :对 131例子宫内膜癌患者中≥ 6 0岁 5 1例 (老年组 )进行回顾性研究并与同期≤ 5 0岁的 35例 (中青年组 )做对照分析。全部手术切除的标本均经病理检查确诊。结果 :老年组与中青年组临床分期 ,Ⅱ期以上的分别为 2 9 4 %(15 / 5 1)和 11 4 %(4/ 35 ) ;组织分级G2 -G3分别为 6 8 6 %(35 / 5 1)和 45 7%(16 / 35 ) ;子宫肌层浸润深度大于 1/ 2的分别为 43 1%(2 2 / 5 1)和 2 0 0 %(7/ 35 ) (P <0 0 1) ;5年存活率分别为 6 6 6 %和 91 4 %(P <0 0 5 )。结论 :老年子宫内膜癌的预后较中青年妇女的子宫内膜癌差 ,与临床分期晚和组织分化差有关。

Analysis of Emdometrial Carcinoma in 51 Older Women

Objective:To analyze the clinical characteristics and histological grading of endometrial carcinoma in older women. Methods:131 patients with endometrial carcinoma were admitted in our hospital from Jan. 1990 to Jan. 2003. Among them, 51 cases were older than 60 years (Older group), and 35 cases were younger than 50 years (Younger group). All of them had pathological diagnosis and clinical-pathological staging according to FIGO's criteria. Results:The amount of patients with advanced staging (stage II to IV) and with pathological grading G2-G3 in older group (29.4% and 68.6%, separatively) was higher than those in younger group (11.4% and 45.7%, respectively). The cases with deeper uterine invasion in older group (43.1%) were higher than those of the younger group (20.0%,P<0.01). The 5 years survival rates were 54.3% and 91.6%, respectively (P<0.05). Conclusions:The clinical staging and pathological characteristics of endometrial carcinoma in older women might be responsible for their poor prognosis.