| 糖尿病对阿尔茨海默病发病风险的Meta分析 |
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| 引用本文： | 聂宏伟,徐勇,张耀东,雷婷,惠晓萍. 糖尿病对阿尔茨海默病发病风险的Meta分析[J]. 现代预防医学, 2010, 37(7) |
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| 作者姓名： | 聂宏伟 徐勇 张耀东 雷婷 惠晓萍 |
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| 作者单位： | 苏州大学放射医学与公共卫生学院社会医学与儿少卫生教研室,苏州,215123 |
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| 摘 要： | [目的]探讨糖尿病对阿尔茨海默病(Alzheimer's Disease)发生的危险性。[方法]通过中国期刊网、HighWire Press、Medline等数据库搜集资料,然后应用RevMan5.0软件对所得资料进行Meta分析,选用随机效应模型进行合并效应量。[结果]经过文章质量的评价,筛选出可用文献9篇,其中包括病例对照研究5篇,队列研究4篇,纳入病例1258人,对照7708人。在对病例-对照文献的分析后得出的结果有显著性(OR=2.27,95%CI:1.39～3.68),而对队列研究的分析结果却与病例对照的结果有一定的差异(OR=1.31,95%CI:0.96～1.80),最后对两类文献资料进行合并分析后得出的结果具有显著性(OR=1.82,95%CI:1.24～2.68)。[结论]糖尿病可能是阿尔茨海默病发生的一个危险因素。
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| 关 键 词： | 糖尿病 阿尔茨海默病 危险因素 Meta分析 |
META-ANALYSIS OF THE ASSOCIATION BETWEEN DIABETES AND THE RISK FOR ALZHEIMER'S DISEASE |
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| NIE Hong-wei,XU Yong,ZHANG Yao-dong,et al.. META-ANALYSIS OF THE ASSOCIATION BETWEEN DIABETES AND THE RISK FOR ALZHEIMER'S DISEASE[J]. Modern Preventive Medicine, 2010, 37(7) |
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| Authors: | NIE Hong-wei XU Yong ZHANG Yao-dong et al. |
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| Affiliation: | NIE Hong-wei,XU Yong,ZHANG Yao-dong,et al.(Department of Social Medicine , Children Hygiene,School of Radiation Medicine , Public Health,Soochow University,Suzhou 215123,China) |
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| Abstract: | [Objective] To study the risk of diabetes to Alzheimer.[Methods] The references were retrived through the databases of CNKI,HighWire Press,Medine and so on,then the random effects model of the meta-Analysis was chosen to analyze the data from references by Revman version 5.0.[Results] There were nine references left after assessed quality,which included five case-control and four cohort of studies.In the data,there were 1 258 cases and 7 708 controls.Meta-analytic evaluation with random effects models resul... |
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| Keywords: | Diabetes Alzheimer's disease Risk fators Meta-analysis |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
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