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Synthesis and relative binding affinity to human steroid receptors of substituted 3-aryloxycoumarins |
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| Authors: | Bakhchinian Robert Terrier François Kirkiacharian Serge Resche-Rigon Michèle Bouchoux Françoise Cérède Evelyne |
| Affiliation: | Laboratoire de Chimie Thérapeutique, Faculté de Pharmacie de PARIS-SUD, 5 rue Jean-Baptiste Clément, F-92296 Cedex, Chatenay Malabry, France. |
| Abstract: | The synthesis of a set of substituted 3-aryloxycoumarins was performed. The study of the relations between their structure and their relative binding affinity to human androgen, progesterone, alpha and beta estrogen receptors was achieved. |
| Keywords: | Coumarins Binding affinity Steroid receptors |
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