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| 全身炎症反应综合征患者血浆血管活性因子变化及临床意义 | |
| 引用本文： | 李银平,沈洪,黎檀实,吴旭辉.全身炎症反应综合征患者血浆血管活性因子变化及临床意义[J].中国急救医学,2000,20(7):398-399. |
| 作者姓名： | 李银平 沈洪 黎檀实 吴旭辉 |
| 作者单位： | 1. 天津市天河医院,300050 2. 北京解放军总医院急诊科 3. 北京海军总医院心内科 |
| 摘 要： | 目的 探讨肿瘤坏死因子－α（ＴＮＦ－α）去甲肾上腺素（ＮＥ），内皮素（ＥＴ），肾上腺髓质素（ＡＤＭ）在全身炎症反应综合征（ＳＩＲＳ）病理过程中的作用。方法 检测３８例不同类型的ＳＩＲＳ（创伤，创伤性休克，感染性休克）患者及１２例健康对照组血浆ＴＮＦ－α，ＮＥ，ＥＴ，ＡＤＭ水平。结果 创伤组，创伤性休克组，感染性休克组与正常对照组血浆ＴＮＦ－α，ＮＥ，ＥＴ，ＡＤＭ浓度相比均明显增加，尤以感染性休克组 |
| 关 键 词： | 全身炎症反应综合征 TNFα 去甲肾上腺素 内皮素 |
Clinical significance of plasma level of vasoactive substances in systemic inflammatory response syndrome |
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| LI Yin-ping,SHEN Hong,LI Tan-shi,et al..Clinical significance of plasma level of vasoactive substances in systemic inflammatory response syndrome[J].Chinese Journal of Critical Care Medicine,2000,20(7):398-399. | |
| Authors: | LI Yin-ping SHEN Hong LI Tan-shi |
| Institution: | LI Yin-ping,SHEN Hong,LI Tan-shi,et al.Tianjing Tianhe Hospital,Tianjing 300050,China [ |
| Abstract: | Objective To investigate the role of tumor necrosis factor-a(TNF-a),norepinephrine (NE),endothelin (ET),adrenomedullin(ADM)in the pathogenesis of systemic inflammatory response syndrome(SIRS).Methods Plasma TNF-a,NE,ET and ADM levels were measured in 38 patients with SIRS .Results Plasma TNF-a,NE,ET and ADM levels were significantly higher in SIRS,especically in sepsis shock than that of healthy controls ( P <0 01) Conclusion The results indicate that TNF-a,NE,ET and ADM plays an important role in the pathophysiology of SIRS. |
| Keywords: | SIRS Sepsis shock TNF-a NE ET ADM |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |