| 食管癌治疗敏感基因单核苷酸多态性 |
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| 引用本文： | 季文豪,凌志强,毛伟敏. 食管癌治疗敏感基因单核苷酸多态性[J]. 国际肿瘤学杂志, 2011, 38(12): 923-926. DOI: 10.3760/cma.j.issn.1673-422X.2011.12.015 |
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| 作者姓名： | 季文豪 凌志强 毛伟敏 |
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| 作者单位： | 浙江省肿瘤医院浙江省肿瘤研究所,杭州,310022 |
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| 基金项目： | 浙江省自然科学基金资助项目，卫生部-浙江省重大科研基金资助项目，浙江省重大科技专项计划项目 |
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| 摘 要： | 研究显示食管癌治疗过程中表现的个体差异与遗传多态性有密切关系.已证实顺铂及5氟尿嘧啶(5-FU)代谢相关基因、凋亡及血管生成相关基因单核苷酸多态性与食管癌治疗敏感性密切相关.
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| 关 键 词： | 食管肿瘤 单核苷酸多态性 |
Therapeutic sensitivity gene SNP in esophageal cancer |
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| JIWen-hao,LING Zhi-qiang,MAO Wei-min. Therapeutic sensitivity gene SNP in esophageal cancer[J]. Journal of International Oncology, 2011, 38(12): 923-926. DOI: 10.3760/cma.j.issn.1673-422X.2011.12.015 |
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| Authors: | JIWen-hao LING Zhi-qiang MAO Wei-min |
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| Affiliation: | Zhejiang Cancer Research Institute, Zhejiang Province Cancer Hospital, 310022 Hangzhou, China |
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| Abstract: | Genetic polymorphisms are thought to be associated with the individual difference in the esophageal cancer treatment.A large number of evidences show that 5-FU and cisplatin metabolism,apoptosis and angiogenesis related gene SNPs are associated with the therapeutic sensitivity of esophageal cancer. |
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| Keywords: | Esophageal neoplasms Single nucleotide polymorphism |
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