| 靶向性溶瘤腺病毒治疗胰腺癌 |
| |
| 引用本文： | 王伟,谭晓华.靶向性溶瘤腺病毒治疗胰腺癌[J].国际肿瘤学杂志,2011,38(9):690-692. |
| |
| 作者姓名： | 王伟 谭晓华 |
| |
| 作者单位： | 山西医科大学第二临床医学院(现工作单位：北京军区总医院生物治疗中心),太原,030001 |
| |
| 摘 要： | 采用溶瘤病毒靶向策略开展胰腺癌基因治疗研究是一个新的发展方向.目前相关研究有分子生物学、基因水平的体外实验和动物模型体内实验、靶向策略等,部分溶瘤腺病毒药物已进入Ⅲ期临床试验.溶瘤腺病毒单独使用或与其他治疗手段联合应用,能够增强抗肿瘤效应.
|
| 关 键 词： | 溶瘤病毒 基因打靶 胰腺肿瘤 |
Targeting oncolytic adenovirus therapy in pancreatic cancer |
| |
| WANG Wei,TAN Xiao-hua.Targeting oncolytic adenovirus therapy in pancreatic cancer[J].Journal of International Oncology,2011,38(9):690-692. |
| |
| Authors: | WANG Wei TAN Xiao-hua |
| |
| Abstract: | Carrying out targeting an oncolytic adenovirus strategy in gene therapy of pancreatic cancer is a new direction.Currently,related research including vitro test and animal models vivo test,targeted strategies on molecular biology and gene level are carried out.Some of oncolytic adenovirus drugs have entered phase Ⅲ clinical trials.Oncolytic adenoviruses alone or in combination with other treatments,can enhanced anti-tumor effect. |
| |
| Keywords: | Oncolytic viruses Gene targeting Pancreatic neoplasms |
| 本文献已被 万方数据 等数据库收录！ |
|
