钼靶对乳腺癌诊断价值的Meta分析

目的 利用Meta分析对钼靶诊断乳腺癌的价值进行系统综合评价.方法 收集1990～2010年国内、外公开发表的关于钼靶诊断乳腺癌的原始文献,并按照制定的评价标准进行筛选,采用固定效应模型、随机效应模型和综合接受者工作特征曲线(SROC)分析方法,综合评价钼靶诊断乳腺癌的准确性.结果 钼靶对乳腺癌诊断的合并灵敏度为84.03%(95%CI:82.04%～86.01%),合并特异度为77.59%(95%CI:72.89%～82.28%),合并后的诊断比值比(DOR)为15.05(95%CI:10.32%～21.95%);SROC曲线下面积(AUC)为0.874,诊断试验准确性指标(TPR)为81.

Meta analysis of diagnostic value of mammography for breast cancer

Objective To apply Meta analysis to process a systematic comprehensive evaluation on the diagnostic value of mammography(MG) for breast cancer.Methods The original literature published in home and abroad on the MG diagnosis of breast cancer from 1990 to 2010 were collected and screened according to the assessment standard.The fixed-effects model,random-effects model and summary receiver operating characteristic curve(SROC) were used to evaluate the accuracy of the mammography for diagnosing breast cancer.Results The pooled sensitivity of MG for diagnosing breast cancer was 84.03%(95% CI:82.04%-86.01%),the pooled specificity was 77.59%(95% CI:72.89%-82.28%),and the pooled diagnostic odds ratio(DOR) was 15.05(95%CI:10.32%-21.95%).The area under the SROC curve was 0.874,the true positive rate(TPR) was 81.62%,which represented the accuracy index of SROC.Conclusion MG has higher accuracy on diagnosis of breast cancer,which is a better imageological method for diagnosis breast cancer.