Factors influencing the time of sentinel node visualization in breast cancer patients using intradermal injection of the radiotracer |
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| Authors: | Aliakbarian Mohsen Memar Bahram Jangjoo Ali Zakavi Seyed Rasoul Reza Dabbagh Kakhki Vahid Aryana Kamran Forghani Mohammad Naser Sadeghi Ramin |
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| Affiliation: | aSurgical Oncology Research Center, Mashhad University of Medical Sciences, Islamic Republic of Iran;bPathology Department, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran;cNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran;dCancer Research Center, Mashhad University of Medical Sciences, Mashhad, Islamic Republic of Iran |
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| Abstract: | BackgroundThe objective of our study was to determine the important factors that have influence on the time of sentinel node visualization using intradermal injection of 99mTc-antimony sulfide colloid.MethodsTwo hundred fifty consecutive patients with the diagnosis of early-stage breast cancer were evaluated. Anterior and lateral views were acquired in various intervals after intradermal injection of the tracer until 180 minutes or visualization of the sentinel node. The effect of several variables on the time of sentinel node visualization was evaluated by univariate and multivariate analyses.ResultsThe time of sentinel node visualization was significantly correlated with age, body mass index (BMI), and interval between biopsy and sentinel node mapping. Standardized beta values for these variables were .1, .3, -.55 respectively.ConclusionsOlder age and higher BMI can result in slow sentinel node visualization. Longer interval between biopsy and sentinel node mapping can be associated with rapid sentinel node detection. |
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| Keywords: | Sentinel 99mTc-antimony sulfide colloid Time of sentinel node visualization Time to previous biopsy Age Body mass index |
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