| 2,4-二硝基苯酚对双层脂膜的效应 |
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| 引用本文： | 沈霞昌,H.Ti Tien.2,4-二硝基苯酚对双层脂膜的效应[J].山东大学学报(医学版),1985(4). |
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| 作者姓名： | 沈霞昌 H.Ti Tien |
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| 作者单位： | 山东医学院物理学教研室，美国密执安州立大学生理和生物物理系 |
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| 摘 要： | 用人工双层脂膜(BLM)模型研究了解偶联剂2,4-二硝基苯酚(DNP)对膜的氧化磷酸化的解偶联作用,其中包括DNP的浓度效应,并绘制了膜的电流-电压曲线,所得结果支持Mitchell的化学渗透假说。
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| 关 键 词： | 二硝基酚类 双层脂膜 解偶联剂 膜电位 |
THE EFFECTS OF 2.4-DINITROPHENOL(DNP) ON BILAYER LIPID MEMBRANE(BLM) |
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| Shen Xiachang.THE EFFECTS OF 2.4-DINITROPHENOL(DNP) ON BILAYER LIPID MEMBRANE(BLM)[J].Journal of Shandong University:Health Sciences,1985(4). |
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| Authors: | Shen Xiachang |
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| Abstract: | The study of uncoupling effects of DNP on oxidative phosphorylation of the membrane has been carried out using the model of artificial BLM. The effects include concentration effect of DNP and pH effect of bathing solution of the membrane. The I-V curve of the membrane has been drawn out. All of the results we got are the evidence of the chemiosmotic hypothesis put forword by Mitchell more than 20 years ago. |
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| Keywords: | Dinitrophenots Bilayer lipid membrane Uncoupling agents Membrane potentials |
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