马拉色菌相关婴儿皮肤病

马拉色菌是人皮肤表面的常驻真菌，能引起婴儿花斑癣，并与婴儿脂溢性皮炎、婴儿特应性皮炎、新生儿头部脓疱病、婴儿及新生儿痤疮的发病相关。这种相关性主要表现在皮损处能检出马拉色菌，且抗真菌治疗有效，在婴儿特应性皮炎的发病中，主要作为抗原。由于婴儿和新生儿的皮肤屏障功能、机体免疫功能等尚不成熟，在患该类疾病时临床表现不典型，较成人有差异，治疗以外用药物为主。

Infantile skin diseases associated with Malassezia species

Malassezia species belong to resident fungi of normal human skin. They can cause infantile pityraisis versicolor, and are related to infantile seborrheic dermatitis, infantile atopic dermatitis, neonatal cephalic pustulosisa, infantile acne and acne neonatroum. Most of the evidence of this association lies in the isolation of malassezia from the lesions and the efficacy of antifungal drugs. Malassezia acts as an allergen in the pathogenesis of infantile atopic dermatitis. Since the barrier and immune function of infantile skin are immature, the clinical features of these diseases in infants are atypical or different from those in adults, and topical treatment is the main choice of management.